Saint Mary’s vs San Francisco Prediction, Picks & Odds for Tonight's College Basketball Game

Saint Mary's has been top-notch, but a long string of road games will make it difficult for the Gaels to cover the 6-point spread in San Francisco tonight.

JD Yonke - Contributor at Covers.com
JD Yonke • Contributor
Feb 6, 2025 • 08:07 ET • 4 min read

NCAAB

Match starts: 10 hrs
SF
45 %
SMC
55 %
EXPERT PICK - SPREAD
San Francisco +6.0 (-110) San Francisco +6.0 (-110)
Read Analysis
Malik Thomas San Francisco Dons NCAA College Basketball
Photo By - Imagn Images.

The Saint Mary’s Gaels put their unblemished conference record on the line when they hit the road to face the San Francisco Dons tonight. 

The Gaels have been a wagon in WCC play, covering nine of its last 10 games, including a 62-58 outright win over Gonzaga on Saturday. But our Saint Mary's vs. San Francisco predictions like the Dons to keep this game within the number.

Read on for our college basketball picks ahead of this 9 p.m. ET tip on Thursday, February 6. 

Saint Mary’s vs San Francisco prediction

My best bet
San Francisco +6 (-110 at bet365)

My analysis
First, let’s talk about how great the Saint Mary’s Gaels have been. Randy Bennett’s squad has won 10 consecutive games, the fourth-longest streak in the country. They are in prime position to capture the regular-season title after toppling rival Gonzaga over the weekend. 

They’re tied for the best rebounding percentage (57.5%) in the nation and play their typical stingy defense. Offensively, five players average at least 9.0 points per game, led by guard Augustas Marciulionis (13.4) and forward Paulius Murauskas (13.1). 

So, why am I fading this seeming juggernaut today? 

It’s a tough scheduling spot. The Gaels are coming off a huge win over Gonzaga and hit the road to play the team that jumped Gonzaga in the standings for second place, at least for now — the San Francisco Dons

San Francisco is a tough out at home. The Dons are a perfect 14-0 at the Sobrato Center, winning four straight by double digits. 

These teams met not long ago and Saint Mary’s ran away 71-51 at home on January 23. USF’s leading scorer, Malik Thomas (19.7 PPG), was limited to eight points on a grotesque 1-for-12 shooting night, including 0-for-5 from downtown. 

It’s unlikely that Thomas will have such a catastrophic night again, especially at home this time around. This will be Saint Mary’s fifth road game in its last seven outings, and the Gaels are on the road again shortly after to face Oregon State in Corvallis on Saturday. 

The Dons should be good enough to capitalize on this scheduling advantage. After such a strong run against the number lately (8-1 ATS in its last nine), Saint Mary’s probably isn’t catching any steep discounts in the market, so I’m opting for the other side.

Saint Mary’s vs San Francisco same-game parlay (SGP)

San Francisco +6.5

Over 131.5

These teams have tended to cash the Over when playing in San Francisco, going 4-0 O/U in the last four games of this series that USF has hosted. 

The first meeting saw 132 points, narrowly coming in below the total of 134. San Francisco was just 14-for-52 from the field (27%) while Saint Mary’s made just a single 3-pointer on five attempts, and was 6-for-14 from the line. 

It’s unlikely that USF will have a similarly disastrous offensive output at home, and Saint Mary’s shooting probably won't bottom out yet again. Even with both of those outcomes in the first matchup, it still would’ve been enough to creep Over the total of 131.5 established for the rematch. 

These teams are 6-2 O/U in the last eight meetings overall.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Saint Mary’s vs San Francisco odds

Saint Mary’s vs San Francisco live odds

Saint Mary’s vs San Francisco opening odds

  • Spread: Saint Mary’s -6 (-110) | San Francisco +6 (-110)
  • Moneyline: Saint Mary’s -275 | San Francisco +225
  • Over/Under: Over 130.5 (-110) | Under 130.5 (-110)

Odds courtesy of bet365

Saint Mary’s vs San Francisco betting trend to know

San Francisco is 4-1 ATS in home games lined within single digits. Find more college basketball betting trends for Saint Mary’s vs. San Francisco.

How to watch Saint Mary’s vs San Francisco

Location The Sobrato Center, San Francisco, CA
Date Thursday, 2-6-2025
Tip-off 9:00 p.m. ET
TV ESPN2

Saint Mary’s vs San Francisco key injuries

Not intended for use in MA.
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JD Yonke
Contributor

JD is a diehard college football fan with five years of experience writing betting and fantasy content for publications such as SportsGrid, Fantasy Points, Fantrax, and Devy Watch. An avid reader, he uses his inclination to look at things with an exhausting and in-depth, analytic viewpoint combined with a love for statistics and metrics to form a well-rounded handicapping approach.

e's an integral member of the niche (but growing!) college fantasy football community, twice traveling to Canton, OH for the Fantasy Football Expo as a member of the CFF King's Classic drafting squad. His specialization in college football DFS and prop betting taught him that there are exploitable markets to be found and that narrowing your focus is integral to being a profitable bettor.

A lifelong Californian who grew up playing baseball, basketball, football, and lacrosse, he's glad to share a passionate love for sports with this wonderful community.

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