Penguins vs Sabres Odds, Picks, and Predictions Tonight: Buffalo Beats Down on Tired Pittsburgh

Pittsburgh is coming off a heartbreaking loss to Boston last night and now has to travel to Buffalo to take on the Sabres. With the Pens set to have a group of tired legs, our NHL betting picks believe Buffalo will pick up the underdog win.

Tony Sartori - Betting Analyst at Covers.com
Tony Sartori • Betting Analyst
Nov 2, 2022 • 12:45 ET • 4 min read

We have an Eastern Conference tilt in Wednesday’s nightcap with the Atlantic Division’s Buffalo Sabres hosting the Metropolitan Division’s Pittsburgh Penguins. Last season, Buffalo won two of the three meetings between these two clubs.

Will the Sabres take care of business once again, or can Pittsburgh grab a victory as a short NHL odds road favorite? Find out in our free NHL betting picks and predictions for the Penguins vs Sabres on Wednesday, November 2.

Penguins vs Sabres best odds

Penguins vs Sabres picks and predictions

The Penguins enter this game amidst a five-game losing streak, and on the second half of a back-to-back where they traveled following an overtime game. This losing streak is likely to continue against an up-and-coming Buffalo team.

Since it is on the second half of a back-to-back, we can expect backup goaltender Casey DeSmith to start between the pipes for Pittsburgh. Over his last two starts against the Sabres, DeSmith is 0-1-1 with a .902 SV% and 2.91 GAA.

In front of DeSmith is a team that ranks 15th in the league in expected goals against per 60 minutes (xGA/60) at 5v5. Additionally, it is dealing with the absence of star defenseman Kris Letang, who missed last night’s game due to an illness.

It is unclear whether he will be ready to go or not in Buffalo, but his absence would be a huge blow for an already average blue line. His absence was certainly felt in Tuesday’s game against the Boston Bruins as the Penguins surrendered six goals.

On the other side, the Sabres enter this contest in strong form following their dominating 8-3 win over the Detroit Red Wings Monday night. In fact, Buffalo has now won five of its last seven games as the team continues to improve under head coach Don Granato.

Because of previous seasons, critics continue to underestimate this up-and-coming club. However, Rasmus Dahlin has finally emerged as the star defenseman he was projected to be, Tage Thompson continues to score at a high clip despite doubters clamouring for regression, and the Sabres have a strong revolving cast of role players that help produce in all three zones to round out a solid hockey team.

At 5v5, Buffalo ranks inside the Top 9 in the league in both goals per 60 minutes (GF/60) and goals against per 60 minutes (GA/60). Backing up this team is the goaltending tandem of Eric Comrie and Craig Anderson.

It is unclear which guy will start in tonight’s matchup, but either is a good option as they both have looked relatively strong to start the year. These teams are trending in two very different directions, and while the Penguins will likely figure it out, I am not confident they will do so on the second half of a back-to-back following a night where they lost a dramatic overtime game.

My best bet: Sabres moneyline (+110 at DraftKings)

Bet NHL bonuses

Looking to do some NHL betting? Here are two of the best bonuses* available:

A) New users at FanDuel can get a no-sweat first bet of up to $1,000! Sign Up Now

B) New users at DraftKings can bet $5 and get $200 in free bets! Sign Up Now

*Eligible USA locations only. Also, check out our full list of best sportsbook promotions for 2022.

Penguins vs Sabres moneyline analysis

My main concern in backing Buffalo in this contest is its thin blue line. Henri Jokiharju is considered week-to-week with a facial fracture, Ilya Lyubushkin is questionable with a lower-body injury, and Mattias Samuelsson is out for several weeks with a lower-body injury.

Regression is likely to hit this group soon, especially considering the injuries on the back end. At 5v5, the Sabres rank just 24th in the league in xGA/60.

However, the regression might hold off for just one more game as the Penguins come into town in awful form. Pittsburgh had to travel for this game following a demoralizing loss to Boston, and some tired legs from the Pens should help out a thin Buffalo defense.

Penguins vs Sabres Over/Under analysis

The Over should also be a strong bet to make in this contest and I plan to hop on that as well. Both of these teams are coming off games where there were 11 total goals scored, which is a product of two strong offenses.

At 5v5, both the Penguins and Sabres rank inside the Top 10 in GF/60 and Top 12 in xGF/60. Meanwhile, both teams could potentially be missing key pieces to their defenses with the absences of Letang, Jokiharju, Samuelsson, and Lyubushkin.

I do not necessarily trust either Casey DeSmith or Eric Comrie, each of which should guarantee to let in at least two goals. It should not be too difficult to come by two-to-three more goals in this contest considering the offensive firepower each team possesses.

Rasmus Dahlin is emerging as the star he was projected to be while Tage Thompson is fighting off the regression that many critics expected from him this year. Meanwhile, Sidney Crosby and Evgeni Malkin need no introduction for Pittsburgh.

Penguins vs Sabres betting trend to know

The Pittsburgh Penguins have lost five straight games. Find more NHL betting trends for Penguins vs Sabres.

Penguins vs Sabres game info

Location: KeyBank Center, Buffalo, NY
Date: Wednesday, November 2, 2022
Puck drop: 7:30 p.m. ET
TV: TNT

Penguins vs Sabres key injuries

Pages related to this topic

Tony Sartori - Covers.com
Betting Analyst

Tony Sartori has written over 1,000 pieces of sports betting content across multiple different media outlets. He covers the NHL, UFC, PGA, NFL and MLB. Tony started part-time while attending the University of Wisconsin-Madison, where he went on to receive a B.A. in Economics and a certificate in Entrepreneurship in 2022. He continues to work full-time in the sports betting landscape.

Due to the variety of sports he covers, Tony is handicapping every day. If he had one piece of betting advice for a new sports bettor, it would be to strictly enforce bankroll management rules for yourself. If you set aside $10,000 for your betting bankroll, then you should generally only be betting between $100 - $500 per play.

Popular Content

Legal Canadian sports betting

Best Canadian betting sites Ontario sports betting
Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo