The Los Angeles Dodgers' title defense continues with an intriguing interleague matchup as they’ll host American League Cy Young Award winner Tarik Skubal and the Detroit Tigers.
Will Skubal be able to shut down the most dangerous lineup in baseball? My Tigers vs. Dodgers predictions like at least one L.A. player to be productive at the plate in Mookie Betts.
Find that and more MLB picks for this game at Dodger Stadium on Thursday, March 27, with first pitch at 7:10 p.m. ET on ESPN.
Tigers vs Dodgers prediction
My Tigers vs Dodgers best bet: Mookie Betts Over 0.5 RBIs (+240 at bet365)
The Los Angeles Dodgers are primed for another monster year. They are coming off a World Series win, and all they did was add another Japanese phenom in Roki Sasaki, an All-Star reliever in Tanner Scott, and the guy who gets the Opening Day start in two-time Cy Young winner Blake Snell.
On top of that, Shohei Ohtani is expected to be back on the mound at some point this season, and the lineup is arguably the best in baseball. But they will be tested right out of the gates as they face off against American League Cy Young Award winner Tarik Skubal and the Detroit Tigers.
The left-handed pitcher was outstanding in 2024, pitching to a 2.39 ERA and an 0.92 WHIP, and led the majors with 228 strikeouts. But the Dodgers were one of the toughest teams against southpaws in baseball.
The Dodgers led the MLB in OPS, wRC+, and home runs when facing lefties in 2024, and Mookie Betts was a big part of that.
Betts was dealing with a well-documented stomach bug that kept him out of the Tokyo Series, which resulted in him losing a lot of weight. But he’s seen some game action since then and is reportedly ready to go for Opening Day.
Betts has crushed lefties during his great career and last season was no different. The eight-time All-Star hit .308 with an .852 OPS vs. southpaws in 2024.
Betts has never faced Skubal, but when you’re hitting behind Ohtani, you’re going to get some pitches to hit and the chance to drive in a bunch of runs.
I know this is a touch matchup, I just don’t know how many times this season we’re going to be able to bet Mookie to drive in a run at a price like this. I’m backing Mookie to do just that on Opening Day.
Tigers vs Dodgers same-game parlay (SGP)
Mookie Betts Over 0.5 RBI
Tarik Skubal Under 17.5 outs recorded
Tommy Edman Over 1.5 H+R+RBI
Skubal is great, but so too is this Dodgers lineup, particularly against left-handed pitchers. And this is a road game on Opening Day. It isn’t out of the question that the Tigers don’t push too hard in this situation. And despite his excellent work last season, Skubal only hit 100 pitches four times.
Our Covers prop projections have Skubal at just 15.9 outs for tonight’s game, so let’s add the Under 17.5 outs to this same-game parlay.
Meanwhile, Tommy Edman might be one of the more overlooked guys in the Dodgers’ stacked lineup, but he’s going to be a big contributor, and it could start on Opening Day. Edman is one of the few guys with solid numbers against Skubal.
Edman is 3-for-8 with a .272 expected batting average against Skubal. I like him to be a table setter for the Dodgers tonight, and am adding the Over 1.5 H+R+RBI to this SGP.
Learn how to bet a same-game parlay with these helpful tips and strategies.
Tigers vs Dodgers odds
Tigers vs Dodgers live odds
Tigers vs Dodgers opening odds
- Moneyline: Detroit +130 | Los Angeles -155
- Run line: Detroit +1.5 (-180) | Los Angeles -1.5 (+150)
- Over/Under: Over 6.5 | Under 6.5
Tigers vs Dodgers trend
The Dodgers hit the Over in 48 of their last 75 games last season for +24.95 Units and a 30% ROI. Find more MLB betting trends for Tigers vs. Dodgers.
How to watch Tigers vs Dodgers and game info
| Location | Dodger Stadium, Los Angeles, CA |
| Date | Thursday, 3-27-2025 |
| First pitch | 7:10 p.m. ET |
| TV | ESPN |
| Tigers starting pitcher | Tarik Skubal (2024: 18-4, 2.39 ERA) |
| Dodgers starting pitcher | Blake Snell (2024: 5-3, 3.12 ERA) |
Tigers vs Dodgers latest injuries
Tigers vs Dodgers weather
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
