Grizzlies vs Spurs Prediction, Picks, and Odds for Tonight’s NBA Game

With the Memphis Grizzlies nearly back at 100% and a favorable matchup looming against the San Antonio Spurs, Kenny Ducey is backing the home favorite to cover in the Alamo City.

Kenny Ducey - Betting Analyst at Covers
Kenny Ducey • Betting Analyst
Jan 15, 2025 • 17:58 ET • 4 min read
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This article contains predictions for an old game!

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The Memphis Grizzlies are finally a bit healthier and have to be feeling good about splitting their last four against some quality opponents. 

With a matchup looming against the struggling San Antonio Spurs, my Grizzlies vs Spurs predictions highlight why the shooting tendencies of both teams should tilt this one in the visitors’ favor.

Let’s dig into my latest NBA picks for Wednesday, January 15.

Grizzlies vs Spurs prediction

My best bet
Grizzlies -2.5 (-115 at bet365)

My analysis

We have two teams here that have played polar opposite basketball of one another; the San Antonio Spurs have been buoyed by their defense of late, while the Memphis Grizzlies have taken a much more offensive-oriented approach.

Memphis has honed in on the mid-range this month, leading the NBA in attempts from that zone, while San Antonio has allowed the majority of shots to come from the rim and has been much more efficient at limiting looks from the outside.

And although the Spurs boast a Top-10 defensive efficiency this month, that may be a little flattering considering their recent run of losses — which includes three losses in their last four games. 

Meanwhile, Memphis has been great across the board in just about every shooting zone this month, and it’s done an excellent job defensively inside the arc. San Antonio has gone ice cold from downtown and hasn’t done a good enough job from any spot on the court to give me confidence in a turnaround tonight.  

When you consider that the Grizzlies are healthier and starting to make their mark on the glass, I'm riding with Memphis to cover this short line. 

Grizzlies vs Spurs same-game parlay

Grizzlies -2.5

Chris Paul Over 1.5 threes

Jaren Jackson Jr. Over 8.5 rebounds

We highlighted the shortcomings of San Antonio’s offense above, but one man who’s been doing a good job of late is Chris Paul.

The veteran is now shooting a comfortable 40% from outside this month, having cashed two or more triples in three straight games. The future Hall-of-Famer will now take on a Grizzlies team ranked second-worst against the 3-pointer in January.  

Meanwhile, Jaren Jackson, Jr. has racked up eight or more boards in four of his last five starts, and the Grizzlies big man should take advantage of a matchup guarding Keldon Johnson — who loves to take the ball to the rim, which should get Jackson into plenty of rebounding opportunities.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Grizzlies vs Spurs odds

Grizzlies vs Spurs live odds

Grizzlies vs Spurs opening odds

  • Spread: Memphis -3.5 | San Antonio +3.5
  • Moneyline: Memphis -170 | San Antonio +130
  • Over/Under: Over 237 | Under 237

Odds courtesy of bet365

Grizzlies vs Spurs spread and Over/Under analysis

  • The spread has made just two moves, hitting three points just after opening on Wednesday morning and 2.5 shortly thereafter.
  • The Grizzlies make up 61% of the tickets and 84% of the money wagered on the spread.
  • The total leaped up 2.5 points just after opening, and after some buy-back in the afternoon, has returned to 239.5.

Grizzlies vs Spurs trend

The Under has accounted for 57% of the total handle despite commanding 66% of the bets. Find more NBA betting trends for Grizzlies vs. Spurs.

How to watch Grizzlies vs Spurs

Location: Frost Bank Center, San Antonio, Texas
Date: Wednesday, 1-15-2025
Tip-off: 8:00 p.m. ET
TV: FDSN SE, FDSN SW

Grizzlies vs Spurs latest injuries

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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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