Louisville vs Boston College NCAAF Picks, Predictions, and Best Bets: Eagles Prove To Be Shough Stoppers

The Louisville offense relies on quarterback Tyler Shough, but our college football betting picks believe Boston College can keep him in check as the Eagles give the Cardinals at least a scare if not an outright loss.

Phil Naessens - Betting Analyst at Covers.com
Phil Naessens • Betting Analyst
Oct 25, 2024 • 16:49 ET • 4 min read
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This article contains predictions for an old game!

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Boston College Eagles CFB Donovan Ezeiruaku
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Get set for an exciting matchup tonight as the Louisville Cardinals meet the Boston College Eagles under the bright lights of Alumni Stadium.

The Cardinals have dropped three of their last four, and my Louisville vs. Boston College predictions expect a tight, low-scoring contest.

Read on as I explain why I like Boston College to make a game of it with my free college football picks for Friday, October 25.

Louisville vs Boston College prediction and best bet

My best bet
Boston College +7.5 (-110 at BetMGM)
Picks made at time of writing may not reflect live odds.

My analysis

The Louisville Cardinals are coming off a 52-45 Saturday home loss to the Miami Hurricanes. Louisville is up against an explosive Boston College Eagles offense with one of the top defenses in the ACC.

Boston College has only lost twice this season by more than seven points. The reason? Boston College's big-play offense has 40 explosive plays for 1,195 yards with a stop unit allowing an ACC fourth-best 20 points per game.

The Boston College O-Unit scores 26 points per game. Explosive plays account for 48% of the Eagles' offense, and they face a Cardinals defense that surrenders 31 plays of 20+ yards and 15 plays of 30 or more yards.

The Eagles defense allows a shade under 21 points and 351 yards per game. They are an opportunistic unit with nine interceptions, allowing 21 points or fewer in their previous four contests. 

Louisville quarterback Tyler Shough is the man behind the potent Cardinals offense. He’s thrown 18 scoring strikes with three interceptions, but he’s up against a defense that surrenders the fourth-fewest passing yards (209) in the ACC with only six TD receptions allowed this season.

I like Boston College to cover the number. Boston College's defense can slow the Cardinals' high-scoring offense. The Eagles have had two extra days on the schedule to prepare, and Louisville is coming off a tough, physical Saturday home loss to the Miami Hurricanes. 

The home team has won each of their last seven meetings. While Boston College may not win this contest, the extra two days of preparation — alongside the Eagles' exceptional defense and big-play offense — can help them cover the spread. 

Louisville vs Boston College same-game parlay (SGP)

Boston College +7.5

Tyler Shough 1+ passing TDs

Under 53.5

Shough’s arm is challenging to keep out of the end zone. The Texas Tech transfer has thrown 54 career TD passes and 1+ scoring strike in six of his previous seven games.

We’ve already discussed the Eagles' above-average passing defense. If the Eagles hold Shough to only one scoring strike, and I believe they will, this contest will finish Under the number. 

Neither side relies heavily on its ground game, and both defenses are above average against the run. The respective defenses are probably better than the offenses, and that should keep this one Under the total.  

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Louisville vs Boston College odds

Louisville vs Boston College live odds

Louisville vs Boston College opening odds

  • Louisville vs. Boston College spread: Boston College +8.5
  • Louisville vs. Boston College moneyline: Louisville -250 | Boston College +200
  • Louisville vs. Boston College Over/Under: 53.5

Odds courtesy of BetMGM

Louisville vs Boston College spread and Over/Under analysis

  • Louisville is 3-4-0 ATS this year. They opened as high as -8.5 (-110), but that number has dipped to a consensus of -7.5 (-110).
  • Boston College is also 3-4-0 ATS. They are 5-2-0 ATS across their past seven meetings with Louisville.
  • Over/Under numbers are on the move. After opening as high as 54 (-110), the total has dipped to as low as 53 (-110).

Louisville vs Boston College betting trend to know

Boston College has hit the Under in nine of its last 13 games (+4.60 Units / 32% ROI). Find more college football betting trends for Louisville vs Boston College.

Louisville vs Boston College game info

Location: Alumni Stadium, Chestnut Hill, MA
Date: Friday, 10-25-2024
Kickoff: 7:30 p.m. ET
TV: ESPN2

Louisville vs Boston College latest injuries

Louisville vs Boston College weather

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Not intended for use in MA.
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Phil Naessens
Betting Analyst

Prior to joining Covers in 2022, Phil Naessens spent 38 years as a resident tennis pro in Las Vegas, Mykonos, and Corfu Greece. He’s the past host of the Phil Naessens Show (Armed Forces Radio), and currently hosts the tennis betting podcast, This Week in Tennis.

Phil is the author of the Betting 101 series (MLB, NFL, NCAAF, and Tennis) and has written for numerous publications including SB Nation, FanSided and Lenny Melnick Fantasy Sports. Phil curates the Chip and Charge Tennis Newsletter and pens a weekly tennis column called “10 Things About the ATP Tour," for Passing Shot Productions. 

His favorite sports to bet on are tennis, MLB, WNBA, Euro men’s and women’s hoops, NCAA sports, NFL, and the NBA. Phil has numerous betting accounts in the US and Europe and his best advice is to line shop for the best value possible.

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