Chiefs vs Bills Predictions, Picks, and Best Bets for NFL Week 11

Jason Logan's NFL picks for Chiefs vs. Bills are calling for Josh Allen to break off a big run to keep Buffalo in the game. However, he sees Patrick Mahomes & Co. remaining unbeaten.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst
Nov 17, 2024 • 13:15 ET • 4 min read
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This article contains predictions for an old game!

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Josh Allen Buffalo Bills NFL
Photo By - Imagn Images. Pictured: Josh Allen takes off with his legs.

The NFL Week 11 schedule is packed with must-watch, must-wager matchups. But none of them are as big as the Kansas City Chiefs taking on the Buffalo Bills at Highmark Stadium today at 4:25 p.m. ET, live on CBS.  

Not only do we have a heavyweight bout between two of the NFL’s top teams, but we get another chapter in the wild rivalry between Patrick Mahomes and Josh Allen.

I run down the spread, total, and player props for this important AFC affair and give my best Chiefs vs. Bills predictions and NFL picks for November 17.

Make sure to also check out our favorite Chiefs vs. Bills props before kickoff!

Chiefs vs Bills prediction

Who will win?

This game opened with Kansas City as a slight -115 favorite on the moneyline, giving an implied win probability of 53.5%. But money on the Bills quickly pushed those odds over the fence. 

As of Thursday, Buffalo is a -135 home favorite, which gives it an implied win probability of almost 57.5%. However, I agree with the initial opinion from the oddsmakers, especially with the injuries to the Bills’ receiving corps.

The Chiefs are 12-5 SU when pegged as an underdog since 2018 and Mahomes will get the best of a Bills defense that has been quietly giving up yardage during this five-game winning streak (20th in opponent success rate per play in that span).

Kansas City wins 24-20.

My best bet
Josh Allen longest rush Over 12.5 yards (+100 at BetMGM)

My analysis

If the Buffalo Bills are going to one-up the Kansas City Chiefs on Sunday, it’ll be because of Josh Allen

Buffalo’s quarterback has stood toe-to-toe with Steve Spagnuolo’s defense in past meetings with Kansas City, and while his passing hasn’t always been sharp, he’s been able to do damage with his legs.

Allen, one of the finest dual-threat QBs in the NFL, has rushed for a total of 382 yards on 71 carries over his seven career clashes with K.C. (regular season and playoffs), picking up 5.3 yards per run.

He has broken off a run 13 or more yards in all but one of those seven matchups with the Chiefs, with longs of 16, 18, and 22 yards. His prop total for longest run in the Week 11 odds sits at 12.5 yards O/U with the Over priced at EVEN.

Given that success on the ground, Allen’s rushing markets are a hot commodity among NFL player props bettors this week, and we’ve seen his total yardage climb from as low as 30.5 yards to 35.5 since hitting the board on Tuesday. His longest run prop has also jumped from 11.5 (Over -130) to 12.5 (Over +100).

On the season, Allen is averaging just over 26 rushing yards per game and has posted runs of 13 or more yards six times — three of which have come in the last two games. His longest run props have bounced between 10.5 and 12.5 yards this season, with Allen going Over those numbers in just four of his 10 outings.

But as we’ve seen in past showdowns with the Chiefs, he’ll be prompted to tuck and run a lot against an aggressive attack which blitzes at a high clip and owns one of the best pressure rates per dropback in the NFL. 

Adding to that need to make gains on the ground is a banged-up Bills’ receiving corps. Buffalo has already ruled out WR Keon Coleman, and both WR Amari Cooper and TE Dalton Kincaid are questionable heading into the weekend. On top of those injuries, Allen’s pass protection could have a hole with right guard Spencer Brown also a question mark.

Allen will get his number called for plenty of designed runs, but where he’s most dangerous is when passing plays break down and he has to improvise with his legs. Given Kansas City’s defensive fortitude and missing pieces in the pass game, Allen will be fighting to keep drives alive.

Chiefs vs Bills same-game parlay

Chiefs +2.5

Josh Allen 25+ rushing yards

Josh Allen anytime TD

The Chiefs have the better defense and with the Bills’ receiving corps dinged up, Kansas City gets the nod on offense as well.

Allen has rushed for an average of 54 yards per game in his seven matchups with Kansas City.

Allen will call his own number when it comes to the red zone, having rumbled for three touchdowns in the two games versus K.C. last year. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Chiefs vs Bills odds

Chiefs vs Bills live odds

Chiefs vs Bills opening odds

  • Spread: Kansas City -1.5 | Buffalo +1.5
  • Moneyline: Kansas City -115 | Buffalo -105
  • Over/Under: Over 46.5 | Under 46.5

Odds courtesy of BetMGM.

Chiefs vs Bills spread and Over/Under analysis

  • Kansas City opened as a 1.5-point road favorite at many books last Sunday night, but early action piled in on the Bills and quickly moved this spread to Buffalo -1.5. From there, respected play on Buffalo kept coming and pumped this spread to -2.5.
  • As for the total, it opened at 46.5 points and has come down a tick to 46, with injury concerns on the Bills' offense anchoring this number. 
  • According to Covers Consensus, 60% of spread picks are taking Buffalo and 66% of total picks are siding with the Over.

Chiefs vs Bills betting trend to know

Kansas City is 12-5 SU and 13-3-1 ATS when pegged as an underdog since 2018. Find more NFL betting trends for Chiefs vs. Bills.

Chiefs vs Bills game info

Location: Highmark Stadium, Orchard Park, NY
Date: Sunday, 11-17-2024
Kickoff: 4:25 p.m. ET
TV: CBS

Chiefs vs Bills latest injuries

Chiefs vs Bills weather

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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst “JLo” has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike.

Since joining the Covers team back in 2005, he’s honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet.

He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous “NFL Underdogs” column and representing the Covers Community at the Super Bowl. While he lives for football season, Jason’s first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns.

On top of being a mainstay in media from coast to coast – WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio – he’s had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers’ flagship podcast, The Sharp 600.

His best advice for bettors new and old is “Handicapping isn’t a ‘one size fits all’ process. The impact and importance of information varies from bet to bet. Treat each wager different than the last.”

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