NFL’s Week 15 slate is all about getting to Sunday's late games.
Save for the Miami Dolphins vs. Houston Texans, all the bangers hit in the 4 p.m. window, including a legit Super Bowl showdown when the Buffalo Bills visit the Detroit Lions.
Let’s share the moneyline odds for each Week 15 game and make our favorite NFL picks.
Week 15 moneyline picks
| Matchup | Pick |
|---|---|
 Rams vs  49ers |
(+114) |
 Ravens vs  Giants |
(-950) |
 Commanders vs  Saints |
(-340) |
 Dolphins vs  Texans |
(+120) |
 Chiefs vs  Browns |
(-205) |
 Jets vs  Jaguars |
(-166) |
 Bengals vs  Titans |
(-205) |
 Cowboys vs  Panthers |
(+110) |
 Colts vs  Broncos |
(-180) |
 Bills vs  Lions |
(+120) |
 Steelers vs  Eagles |
(+195) |
 Patriots vs  Cardinals |
(-130) |
 Buccaneers vs.  Chargers |
(-155) |
 Packers vs  Seahawks |
(+124) |
 Bears vs  Vikings |
(-310) |
 Falcons vs  Raiders |
(-238) |
Lines courtesy of DraftKings as of 12-11.
Expert Week 15 moneyline picks
Rams vs 49ers
Rams +114
Yes, the dinged-up San Francisco 49ers laid the wood to the Bears in Week 14, and Kyle Shanahan owns a 10-4 record over good buddy Sean McVay.
But the Los Angeles Rams just went toe-to-toe with Josh Allen and came away with a W. Matt Stafford, Puka Nacua, Cooper Kupp and Kyren Williams are a load right now, and they can expose a compromised Niners unit.
Ravens vs Giants
Ravens -950
This won’t be pretty, as the Baltimore Ravens shouldn’t be in any mood to mess around. Any more slippage and there’s a chance they could slide all the way to 7th in the AFC playoff picture.
New York allows 141.7 rush yards per game which ranks 29th. Baltimore runs wild.
Read our full Ravens vs. Giants predictions.
Commanders vs Saints
Commanders -340
The New Orleans Saints have won three of four, but those wins have come against the Giants, Browns, and Falcons. The Washington Commanders have had a week off to get healthy, and they post 28.9 points per game, the fourth-best mark in the NFL.
New Orleans doesn’t have the firepower to keep up.
Read our full Commanders vs. Saints predictions.
Dolphins vs Texans
Dolphins +120
There’s no margin for error for the Miami Dolphins, who’ve reeled off wins in four of their last five with the next stop against the Houston Texans.
The only good news for 8-5 Houston is they play in the crummy AFC South and would need the wheels to absolutely fall off to lose that grip.
Miami has scored 32+ points in three of its last four. They outscore their problems for at least one more week.
Read our full Dolphins vs. Texans predictions.
Chiefs vs Browns
Chiefs -205
Speaking of not pretty, the Kansas City Chiefs did just enough (again) to outlast the Chargers to clinch the AFC West.
They play with their food again vs. the 3-10 Cleveland Browns and annoyingly walk away with a win that may be closer than it ought to be and doesn't feel representative of a dominant 13-1 team.
Read our full Chiefs vs. Browns predictions.
Jets vs Jaguars
Jets -166
The Jacksonville Jaguars snapped a five-game skid with an uninspiring 10-6 win over the Titans, while the New York Jets collapsed to lose their fourth straight and ninth in the last 10.
But even the dysfunctional Jets can stop Mac Jones from winning back-to-back games.
Read our full Jets vs. Jaguars predictions.
Bengals vs Titans
Bengals -205
There’s life support, and then there’s the Cincinnati Bengals’ playoff hopes, which stayed alive with a win over the Cowboys Monday night.
Joe Burrow will add to his league-leading passing yards and TD pass totals for a Cincy win and keep that sliver of postseason hope alive.
Read our full Bengals vs. Titans predictions.
Cowboys vs Panthers
Cowboys +110
How bad are the Dallas Cowboys? It’s Week 15, and they are the first team the Carolina Panthers have been favored to beat this entire NFL season.
Still, if Dallas’ defense can make life hell for Joe Burrow, what can it do against Bryce Young?
Read our full Cowboys vs. Panthers predictions.
Colts vs Broncos
Broncos -180
The Denver Broncos have cleaned up against the weak part of their schedule, running a perfect 7-0 record against teams with losing records.
They’ve also won four of their last five at home.
Denver’s scoring defense is second-best in the NFL and should play a role in shutting down an erratic Anthony Richardson.
Read our full Colts vs. Broncos predictions.
Bills vs Lions
Bills +120
The two highest-scoring teams in the NFL collide in what could be a legit preview of the Super Bowl (if the Chiefs don’t go and screw things up).
Josh Allen is coming off a mammoth six-touchdown (three passing, three rushing) performance that ended in a loss, but may have cemented his first MVP trophy.
Meanwhile, the Detroit Lions are riding an 11-game win streak, including five straight at Ford Field.
Allen and the Buffalo Bills played giant killer in Week 11, handing KC its first loss of the year. In another absolute shootout, Buffalo assumes the role again.
Read our full Bills vs. Lions predictions.
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Steelers vs Eagles
Steelers +195
If there’s one thing Mike Tomlin won’t allow, it’s Saquon Barkley to go off.
The Pittsburgh Steelers own the fourth-best run defense, allowing 91.5 yards, which will challenge the Philadelphia Eagles’ top-rated run offense that churns out 190.5 yards per game.
If they neutralize the run, Philly’s pop-gun pass attack gets exposed, and Pittsburgh orchestrates an ugly, low-scoring road win, ending the Eagles’ nine-game win streak.
Read our full Steelers vs. Eagles predictions.
Patriots vs Cardinals
Cardinals -130
The New England Patriots are the second-worst team in the league and should be the get-right potion for the Arizona Cardinals and Kyler Murray, whose game has fallen off a cliff at the worst time.
Under Murray’s guidance, the Cards have averaged just 15.3 points per game across a three-game losing skid, throwing for just three TDs against five interceptions.
At 6-7, they’re just about in win-out mode for hopes of securing a playoff berth.
Read our full Patriots vs. Cardinals predictions.
Buccaneers vs Chargers
Chargers -155
The Los Angeles Chargers are the only team with a winning record in a cream-puff, home-stretch schedule for the Tampa Bay Buccaneers, who have the inside track on the NFC South crown.
The Chargers are the latest victims of a KC close defeat, but they need to keep winning to stay in the playoff mix.
Some offense would be nice: LA has scored 23 points or less in each of its last three games.
Read our full Buccaneers vs. Chargers predictions.
Packers vs Seahawks
Seahawks +124
The Seattle Seahawks have won four in a row, and a fifth over the Green Bay Packers would go a long way to clinching the NFC West crown.
Green Bay has won five of the last six against the ‘Hawks but are 0-4 in the last four at Seattle.
Read our full Packers vs. Seahawks predictions.
Bears vs Vikings
Vikings -310
At 11-2, the Minnesota Vikings can still sneak past the Lions should Detroit stumble.
They’ve won six of seven against the Chicago Bears and should roll Monday night.
Falcons vs Raiders
Falcons -238
Kirk Cousins played better against Minnesota (there was nowhere to go but up), and the Atlanta Falcons are still in the NFC South title chase.
Raheem Morris is sticking by the embattled vet. Meanwhile, Aiden O'Connell's run as Las Vegas Raiders QB is done with a knee injury, so Vegas is turning to former Falcon Desmond Ridder.
Not that anything changes — Raiders should bow out on this Monday Night stinker.
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