Colorado vs Houston Prediction, Picks & Odds for Today's Big 12 Tournament Basketball Game

While the Buffaloes may fall short of advancing past the powerhouse Cougars, Colorado should keep it competitive — at least in the early stages.

Douglas Farmer - Betting Analyst at Covers
Douglas Farmer • Betting Analyst
Mar 13, 2025 • 12:23 ET • 4 min read
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This article contains predictions for an old game!

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The Colorado Buffaloes aim for their third consecutive upset as they face the Houston Cougars this afternoon.

Although my Colorado vs. Houston predictions ultimately see no path to that outcome, the Buffaloes may keep this closer than expected.

Find out more in my college basketball picks for Thursday, March 13. 

Colorado vs Houston prediction

Who will win Colorado vs Houston?

Don't get it twisted; Houston will win. 

The Cougars have lost just once since the start of December — a one-point defeat to Texas Tech in overtime. Their only loss this season to a team outside Ken Pomeroy’s Top 10 also came in OT against San Diego State.

For context, Pomeroy currently sees the Aztecs as nearly eight points better than Colorado.

My best bet: Colorado 1H +10.5 (-115 at bet365)

My analysis
Colorado had no business winning on Wednesday. It trailed by seven entering the final 10 minutes of the game, having scored just 14 points in the first half of the second half. The Buffaloes then poured in 30 points in the final 10 minutes to pull out a seven-point win. West Virginia should be embarrassed by giving up a 15-0 run to a team that had not scored 15 points in any of the first three 10-minute segments of the game.

And that is not solely because the Mountaineers doing so cost yours truly a handful of bets.

It was an abdication of defense, one that Houston will not commit, not with the best defense in the Big 12 and the No. 2 defense in the country ranking behind only Tennessee’s.

But Colorado found that momentary offense, and if any momentum whatsoever carries forward, the Buffaloes should stay within range of the Cougars in the first half. Colorado is about to play its third game in the T-Mobile Center this week while Houston makes its debut. That should not provide a massive advantage, but it does add to the Buffaloes’ sense of urgency, a comfort level in the confines that the Cougars may take a minute or two to find.

These two teams met just more than a month ago, a casual 10-point Houston win that was only a four-point game at halftime. That kind of “casual” description can apply to a lot of the Cougars’ last few months. They have not been oft-tested.

In the last two months, Houston has gone 2-6 against the spread as a double-digit favorite, though winning each game. Usually, the Cougars ease up late, but in a midafternoon game after five days off, it is more likely they take some time to get going today.

Colorado vs Houston same-game parlay (SGP)

Colorado 1H +10.5

Colorado team total Under 54.5

1H Under 59.5

This same-game parlay is somehow both logical and counterintuitive. Combining Colorado’s team total Under 54.5 with a first half Under 59.5 is obvious; one helps the other. Mixing Colorado’s team total Under 54.5 with Colorado covering the first half spread of +10.5 is counterintuitive, the latter arguing against the former.

However, all aspects suggest Houston will start the game slowly before showing its true defensive ferocity. Finding three legs that can fit together with that one thought provides value at +475.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Colorado vs Houston odds

Colorado vs Houston live odds

Colorado vs Houston opening odds

  • Spread: Colorado +17.5 | Houston -17.5
  • Moneyline: Colorado +1000 | Houston -2000
  • Over/Under: Over 127 | Under 127

Odds courtesy of bet365

Colorado vs Houston betting trend to know

The Cougars went 1-3-1 ATS in the last three weeks, four of those games also cashing their Unders. Find more college basketball betting trends for Colorado vs. Houston.

How to watch Colorado vs Houston

Location T-Mobile Center, Kansas City, MO
Date Thursday, 3-13-2025
Tip-off 3:00 p.m. ET
TV ESPN2

Colorado vs Houston key injuries

Not intended for use in MA.
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Douglas Farmer
Betting Analyst

Douglas Farmer spends his days thinking about college football and his nights thinking about the NBA. His betting habits and coverage follow that same pattern. He covered Notre Dame football for various outlets from 2008 to 2024, most notably spending eight seasons as NBC Sports’ beat writer on the Irish. That was also when his gambling focus took off. Knowing there were veteran beat writers with three decades more experience than he had, Douglas found his niche by best recognizing Notre Dame’s standing in each year’s national landscape, a complex tapestry most easily understood and remembered via betting odds.

In 2021, that interest created a freelance opportunity with Covers, a role that eventually led to Douglas joining the company full-time in 2023. In the fall, Douglas will place five or six dozen bets each week, a disproportionate amount via BetRivers because the operator tends to have lines slightly different than the rest of the market. The same can be said of Circa Sports’ futures markets.

While Douglas is an avid NBA fan and covers the league throughout the year, the vast majority of his bets are on college football, because that is the biggest key to sports betting: Know what you do not know.

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