Cardinals vs Broncos Prediction, Picks & Odds for This Week’s NFL Preseason Game

With Sunday's dress rehearsal at Mile High Stadium featuring a lack of key starters, Sam Farley anticipates a low-scoring battle between Arizona and Denver in their preseason finale.

Sam Farley - Betting Analyst at Covers.com
Sam Farley • Betting Analyst
Aug 24, 2024 • 13:38 ET • 4 min read
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This article contains predictions for an old game!

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Sunday’s matchup between the Arizona Cardinals and Denver Broncos gives us a final chance to see these teams before the regular season, although both will be without their starting quarterbacks and key starters. 

That has our Cardinals vs. Broncos predictions anticipating a low-scoring affair in our latest NFL picks for August 25. 

Cardinals vs Broncos prediction

My best bet
Under 33.5 (-105 at FanDuel)

My analysis

It’s been a pleasing summer for the Denver Broncos, who have seen rookie Bo Nix cement himself as the team’s starter. This year’s 12th overall pick has played lights-out during the preseason at camp and locked down that starting spot. However, that means that he will sit out Saturday's preseason finale versus the Arizona Cardinals

Without Nix, the team has managed just one passing touchdown from Zach Wilson, while Jarrett Stidham has tossed two interceptions and has yet to throw for any scores.

The Cardinals will also continue to sit Kyler Murray, who has yet to play a single snap this preseason. That means their snaps will be split between Clayton Tune and Desmond Ridder, with Tune expected to start. Those two have failed to get this offense going through two games, sporting just one TD pass altogether.

The Cardinals have failed to reach 15+ points in their first two exhibition matches, and if they maintain those numbers, the Broncos would need to put up 20 points to hit the Over in this matchup. I'm taking the Under, which has already dropped three points from its opening line of 36.5.

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Cardinals vs Broncos odds

Cardinals vs Broncos live odds

Cardinals vs Broncos opening odds

  • Spread: Arizona +3.5 (-115) | Denver -3.5 (-105)
  • Moneyline: Arizona +145 | Broncos -175
  • Over/Under: Over 36.5 (-110) | Under 36.5 (-110)

Cardinals vs Broncos betting trend to know

Heading into Sunday at 2-0, this marks Sean Payton's second straight winning preseason as head coach in Denver. Find more NFL betting trends for Cardinals vs Broncos.

Cardinals vs Broncos game info

Location: Empower Field at Mile High, Denver, CO
Date: Sunday, 8-25, 2024
Kickoff: 4:30 p.m. ET
TV: NFL+

Cardinals vs Broncos weather

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Betting Analyst

Sam is based in the United Kingdom, where he grew up living and breathing soccer, before discovering - and playing - a different kind of football at the University of Bristol. He’s worked in the media covering soccer and the NFL for the better part of a decade, and has been a regular on the Matchbook NFL Podcast. His work has also appeared in a wide range of publications including The Telegraph, The Independent, VICE, and MSN.

The search for great betting value is a daily one, and Sam always hunts out big prices with a particular focus on player props. Sam’s best advice for bettors is to track their bets on a spreadsheet, that way you can keep an eye on your P&L but also the types of bets and sports that you are most successful in. He also recommends using a variety of different sportsbooks, with bet365, Betfair and Paddy Power amongst his favorites.

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