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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 25, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

TB logo
TB
TB

3.05 @ 4.70

PHI
PHI logo
PHI

Rays vs Phillies · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TB logo
TB
TB

3.05

+140

o6.5 -114

+1.5 -170

PHI logo
PHI
PHI

4.70

-162

u6.5 +100

-1.5 +150

Pittsburgh @ Detroit
Matchup Stats

Predicted Score

PIT logo
PIT
PIT

4.29 @ 4.17

DET
DET logo
DET

Pirates vs Tigers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

PIT logo
PIT
PIT

4.29

-105

o7.5 -125

-1.5 +160

DET logo
DET
DET

4.17

-105

u8.5 -130

+1.5 -182

NY Mets @ Washington
Matchup Stats

Predicted Score

NYM logo
NYM
NYM

4.37 @ 4.73

WAS
WAS logo
WAS

Mets vs Nationals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

NYM logo
NYM
NYM

4.37

-130

o7.5 -137

-1.5 +130

WAS logo
WAS
WAS

4.73

+115

u8.5 -124

+1.5 -149

Cincinnati @ Toronto
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

3.50 @ 4.01

TOR
TOR logo
TOR

Reds vs Blue Jays · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CIN logo
CIN
CIN

3.50

+116

o7.5 -112

+1.5 -190

TOR logo
TOR
TOR

4.01

-130

u7.5 +100

-1.5 +172

Atlanta @ Miami
Matchup Stats

Predicted Score

ATL logo
ATL
ATL

4.34 @ 4.56

MIA
MIA logo
MIA

Braves vs Marlins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

ATL logo
ATL
ATL

4.34

-124

o7.5 -141

-1.5 +135

MIA logo
MIA
MIA

4.56

+106

u8.5 -122

+1.5 -157

Cleveland @ Kansas City
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

4.14 @ 3.80

KC
KC logo
KC

Guardians vs Royals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CLE logo
CLE
CLE

4.14

-136

o7.5 -112

-1.5 +127

KC logo
KC
KC

3.80

+120

u8.0 -125

+1.5 -143

Colorado @ Chi. White Sox
Matchup Stats

Predicted Score

COL logo
COL
COL

3.74 @ 5.04

CHW
CHW logo
CHW

Rockies vs White Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

COL logo
COL
COL

3.74

+194

o7.5 -130

+1.5 -114

CHW logo
CHW
CHW

5.04

-225

u8.5 -125

-1.5 +100

St. Louis @ Milwaukee
Matchup Stats

Predicted Score

STL logo
STL
STL

3.69 @ 4.17

MIL
MIL logo
MIL

Cardinals vs Brewers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

STL logo
STL
STL

3.69

+151

o8.0 -115

+1.5 -140

MIL logo
MIL
MIL

4.17

-172

u8.5 -113

-1.5 +130

Texas @ Minnesota
Matchup Stats

Predicted Score

TEX logo
TEX
TEX

4.21 @ 3.61

MIN
MIN logo
MIN

Rangers vs Twins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TEX logo
TEX
TEX

4.21

-108

o7.5 -114

-1.5 +160

MIN logo
MIN
MIN

3.61

-108

u7.5 -103

+1.5 -182

Houston @ Athletics
Matchup Stats

Predicted Score

HOU logo
HOU
HOU

6.33 @ 5.25

ATH
ATH logo
ATH

Astros vs Athletics · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

HOU logo
HOU
HOU

6.33

--

--

--

ATH logo
ATH
ATH

5.25

--

--

--

Arizona @ San Diego
Matchup Stats

Predicted Score

AZ logo
AZ
AZ

4.23 @ 4.20

SD
SD logo
SD

Diamondbacks vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

AZ logo
AZ
AZ

4.23

+120

o7.0 -115

+1.5 -190

SD logo
SD
SD

4.20

-130

u7.5 -112

-1.5 +172

LA Angels @ Seattle
Matchup Stats

Predicted Score

LAA logo
LAA
LAA

3.32 @ 3.56

SEA
SEA logo
SEA

Angels vs Mariners · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAA logo
LAA
LAA

3.32

+115

o6.5 -135

+1.5 -200

SEA logo
SEA
SEA

3.56

-130

u7.0 -118

-1.5 +180

LA Dodgers @ San Francisco
Matchup Stats

Predicted Score

LAD logo
LAD
LAD

5.92 @ 2.53

SF
SF logo
SF

Dodgers vs Giants · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAD logo
LAD
LAD

5.92

-375

o7.0 -125

-2.5 -115

SF logo
SF
SF

2.53

+305

u7.5 -123

+2.5 +110

Chicago Cubs image thumbnail CHC @ Boston Red Sox image thumbnail BOS Fri, Sep 25 • 1:05 PM ET
Total Home Runs
Jarren Duran logo
Jarren Duran o0.5 Total Home Runs (+1500)
Projection 0.1
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 4 out of 5
When it comes to his overall offensive skill, Jarren Duran ranks in the 77th percentile according to the leading projections (THE BAT X).. Batting from the opposite that Clay Holmes throws from, Jarren Duran will have an advantage today.. Jarren Duran has a 93rd percentile opposite-field rate on his flyballs (36%) and sets up very well considering he'll be hitting them towards MLB's shallowest LF fences in today's matchup.. Home field advantage typically bolsters hitter metrics in all categories, and Jarren Duran will hold that advantage in today's game.
View Pick
Tampa Bay Rays image thumbnail TB @ Philadelphia Phillies image thumbnail PHI Fri, Sep 25 • 6:40 PM ET
Total RBIs
J.T. Realmuto logo
J.T. Realmuto o0.5 Total RBIs (+240)
Projection 0.43
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects J.T. Realmuto in the 85th percentile when estimating his batting average ability.. J.T. Realmuto will benefit from the home field advantage today, which should boost all of his stats.
Total RBIs
Bryce Harper logo
Bryce Harper o0.5 Total RBIs (+190)
Projection 0.7
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
According to the leading projection system (THE BAT X), Bryce Harper ranks as the 9th-best hitter in the league.. Bryce Harper is penciled in 3rd in the batting order today.. Hitting from the opposite that Freddy Peralta throws from, Bryce Harper will have the upper hand in today's matchup.. Bryce Harper has an 80th percentile opposite-field rate on his flyballs (34%) and has the good fortune of hitting them in the direction of MLB's 10th-shallowest LF fences today.. Bryce Harper will possess the home field advantage in today's game, which figures to bolster all of his stats.
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Pittsburgh Pirates image thumbnail PIT @ Detroit Tigers image thumbnail DET Fri, Sep 25 • 6:40 PM ET
Total RBIs
Spencer Torkelson logo
Spencer Torkelson o0.5 Total RBIs (+240)
Projection 0.56
Best Odds
Pick made: 37 seconds ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Spencer Torkelson in the 93rd percentile when estimating his home run talent.. Spencer Torkelson is projected to bat 3rd in the lineup today, which would be an upgrade from his 64% rate of hitting in the bottom-half of the batting order this season.. Among every team playing today, the 2nd-weakest outfield defense is that of the Pittsburgh Pirates.. Spencer Torkelson will possess the home field advantage in today's matchup, which figures to bolster all of his stats.
Hits+Runs+RBIs
Spencer Torkelson logo
Spencer Torkelson o1.5 Hits+Runs+RBIs (+155)
Projection 1.81
Best Odds
Pick made: 37 seconds ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Spencer Torkelson in the 93rd percentile when estimating his home run talent.. Spencer Torkelson is projected to bat 3rd in the lineup today, which would be an upgrade from his 64% rate of hitting in the bottom-half of the batting order this season.. Among every team playing today, the 2nd-weakest outfield defense is that of the Pittsburgh Pirates.. Spencer Torkelson will possess the home field advantage in today's matchup, which figures to bolster all of his stats.
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Cincinnati Reds image thumbnail CIN @ Toronto Blue Jays image thumbnail TOR Fri, Sep 25 • 7:07 PM ET
Total RBIs
Vladimir Guerrero Jr. logo
Vladimir Guerrero Jr. o0.5 Total RBIs (+170)
Projection 0.6
Best Odds
Pick made: 4 minutes ago
EV Model Rating
Star rating: 3 out of 5
When estimating his batting average talent, Vladimir Guerrero Jr. is projected as the 4th-best batter in MLB by the leading projection system (THE BAT X).. Vladimir Guerrero Jr. is penciled in 3rd on the lineup card today.. Vladimir Guerrero Jr. will hold the platoon advantage against Nick Lodolo today.. Vladimir Guerrero Jr. hits a high percentage of his flyballs to center field (38.7% — 89th percentile) and is fortunate to face the game's 10th-shallowest CF fences in today's game.. Vladimir Guerrero Jr. will possess the home field advantage in today's game, which ought to improve all of his stats.
Total RBIs
Kazuma Okamoto logo
Kazuma Okamoto o0.5 Total RBIs (+175)
Projection 0.57
Best Odds
Pick made: 4 minutes ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Kazuma Okamoto in the 95th percentile as it relates to his home run skill.. Kazuma Okamoto is projected to bat 5th in the lineup in today's game.. Kazuma Okamoto will have the handedness advantage against Nick Lodolo today.. Kazuma Okamoto will possess the home field advantage today, which ought to boost all of his stats.
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Atlanta Braves image thumbnail ATL @ Miami Marlins image thumbnail MIA Fri, Sep 25 • 7:10 PM ET
Strikeouts Thrown
Eury Perez logo
Eury Perez o4.5 Strikeouts Thrown (-130)
Projection 5.9
Best Odds
Pick made: 40 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT) projects Eury Perez in the 91st percentile when it comes to his strikeout ability.. Eury Perez has averaged 92.3 adjusted pitches per GS this year, placing in the 78th percentile.. Given that groundball hitters are less effective against groundball pitchers, Eury Perez (40.7% GB% according to the leading projection system, THE BAT) is well-situated in this matchup with 3 GB hitters in the opposition's projected batting order.. Eury Perez will benefit from the home field advantage today, which ought to boost all of his stats in all categories.
View Pick
Cleveland Guardians image thumbnail CLE @ Kansas City Royals image thumbnail KC Fri, Sep 25 • 7:40 PM ET
Moneyline
Cleveland Guardians image thumbnail CLE (-137)
Best Odds
Pick made: 3 hours ago
Chris Vasile logo
Chris Vasile
Publishing Editor

I’m backing Cleveland behind Gavin Williams, who enters with a 3.63 ERA, 1.08 WHIP, and 244 strikeouts in 181 innings. Kansas City counters with Noah Cameron, but the bigger edge comes once the starters leave. The Royals’ bullpen has been a problem all season, while Cleveland owns a 3.75 team ERA. With the Guardians still fighting for the AL Central, I’ll trust the better pitching staff in a meaningful game.

Hits+Runs+RBIs
Jac Caglianone logo
Jac Caglianone o1.5 Hits+Runs+RBIs (+110)
Projection 1.96
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 3 out of 5
When estimating his home run ability, Jac Caglianone ranks in the 83rd percentile according to the leading projection system (THE BAT X).. Jac Caglianone is penciled in 3rd in the batting order today.. This game is projected to have the highest humidity on the slate (84%); there is a small yet noteworthy connection with increased offense (and decreased Ks) when the weather is humid.. Batting from the opposite that Gavin Williams throws from, Jac Caglianone will have the upper hand in today's game.. Jac Caglianone will benefit from the home field advantage in today's matchup, which figures to bolster all of his stats.
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Colorado Rockies image thumbnail COL @ Chicago White Sox image thumbnail CHW Fri, Sep 25 • 7:40 PM ET
Total Bases
Ezequiel Tovar logo
Ezequiel Tovar o1.5 Total Bases (+275)
Projection 1.19
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 4 out of 5
Hits+Runs+RBIs
Mickey Moniak logo
Mickey Moniak o1.5 Hits+Runs+RBIs (+180)
Projection 1.43
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 3 out of 5
When it comes to his home run ability, Mickey Moniak ranks in the 92nd percentile according to the leading projection system (THE BAT X).. Mickey Moniak will have the benefit of the platoon advantage against Sean Burke today.. Mickey Moniak pulls a high percentage of his flyballs (39.1% — 96th percentile) and sets up very well considering he'll be hitting them towards MLB's 9th-shallowest RF fences in today's matchup.
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St. Louis Cardinals image thumbnail STL @ Milwaukee Brewers image thumbnail MIL Fri, Sep 25 • 7:40 PM ET
Total RBIs
Jordan Walker logo
Jordan Walker o0.5 Total RBIs (+180)
Projection 0.59
Best Odds
Pick made: 4 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Jordan Walker in the 91st percentile when assessing his overall offensive skill.. Jordan Walker is penciled in 3rd on the lineup card in this matchup.. Jordan Walker will have the handedness advantage over Robert Gasser in today's game... and the cherry on top, Gasser has a large platoon split.. Jordan Walker hits a high percentage of his flyballs to center field (40.4% — 98th percentile) and will have a big advantage facing the game's 8th-shallowest CF fences today.
Total Bases
Joey Ortiz logo
Joey Ortiz u1.5 Total Bases (-240)
Projection 0.77
Best Odds
Pick made: 17 minutes ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Joey Ortiz in the 24th percentile when assessing his home run talent.. Joey Ortiz is projected to hit 9th in the batting order in this game.. The weather report predicts the most favorable pitching conditions of all games on the slate today, as it relates to temperature and humidity.. Michael McGreevy will have the benefit of the platoon advantage against Joey Ortiz in today's game.. Joey Ortiz has a 96th percentile opposite-field rate on his flyballs (37.2%) and has the misfortune of hitting them towards baseball's 7th-deepest RF fences today.
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Texas Rangers image thumbnail TEX @ Minnesota Twins image thumbnail MIN Fri, Sep 25 • 8:10 PM ET
Total Bases
Josh Bell logo
Josh Bell u1.5 Total Bases (-210)
Projection 0.81
Best Odds
Pick made: 6 minutes ago
EV Model Rating
Star rating: 3 out of 5
View Pick
Arizona Diamondbacks image thumbnail AZ @ San Diego Padres image thumbnail SD Fri, Sep 25 • 9:40 PM ET
Moneyline
Arizona Diamondbacks image thumbnail AZ (+116)
Best Odds
Pick made: 4 hours ago
Jon Metler logo
Jon Metler
Betting Analyst

The Arizona Diamondbacks are trading at 46% on Polymarket, and I'm hitting the button at that price, as I make them closer to 50% against the San Diego Padres. You can't have your back against the wall much more than the Diamondbacks do this weekend, as they basically need a sweep to have any hope of making the postseason. That should lead to their roster being managed like they're playing an elimination game, but I also really like the matchup for Brandon Pfaadt. The heart of the Padres' lineup is loaded with right-handed bats, and that's not a problem for Pfaadt, who has held right-handed hitters to a .599 OPS this season. His hard, sweeping slider runs away from the barrels of right-handed hitters, giving him a pitch that can neutralize the strength of San Diego's lineup. That's why the Diamondbacks have my attention at this price.

View Pick
Los Angeles Dodgers image thumbnail LAD @ San Francisco Giants image thumbnail SF Fri, Sep 25 • 10:15 PM ET
Total Bases
Kyle Tucker logo
Kyle Tucker o1.5 Total Bases (+150)
Projection 1.62
Best Odds
Pick made: 8 minutes ago
EV Model Rating
Star rating: 3 out of 5
When assessing his overall offensive skill, Kyle Tucker ranks in the 94th percentile according to the leading projections (THE BAT X).. Kyle Tucker is penciled in 5th in the batting order in this game.. The wind projects to be blowing out to RF at 13.4-mph in this contest, the best of the day for hitters.. Kyle Tucker will hold the platoon advantage against Yunior Marte today.. The San Francisco Giants have just 1 same-handed RP in their bullpen, so Kyle Tucker can likely count on never losing the platoon advantage against the 'pen all game.
Total Bases
Shohei Ohtani logo
Shohei Ohtani o1.5 Total Bases (-120)
Projection 2.13
Best Odds
Pick made: 24 minutes ago
EV Model Rating
Star rating: 3 out of 5
According to the leading projection system (THE BAT X), Shohei Ohtani ranks as the 4th-best batter in Major League Baseball.. Shohei Ohtani is projected to bat 1st on the lineup card in this game.. The wind projects to be blowing out to RF at 13.4-mph in this contest, the best of the day for hitters.. Batting from the opposite that Yunior Marte throws from, Shohei Ohtani will have an edge in today's matchup.. The San Francisco Giants have just 1 same-handed RP in their bullpen, so Shohei Ohtani can likely count on holding the advantage against every reliever all game.
View 5 Picks

What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

What kinds of MLB picks do we make?

Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.