MLB Picks

Get free expert and computer MLB picks for every game on March 26, 2026. With over 25 years of betting experience, our analysts and predictive models help you find the best value.

Minnesota Twins logo MIN @ Baltimore Orioles logo BAL Thu, Mar 26 • 3:05 PM ET
3 Expert Picks 3 Computer Picks
Total Home Runs
Pete Alonso logo Pete Alonso o0.5 Total Home Runs (+290)
Best Odds
Pick made: 2 hours ago
Ed Scimia image
Ed Scimia
Betting Analyst

Alonso has hit at least 34 home runs in every full season of his career, including going for 38 bombs with an .871 OPS, his highest OPS since his rookie season. Joe Ryan gave up seven homers in his last four starts of 2025, and I like Alonso to get off to a fast start in his new home.

Moneyline
Baltimore Orioles logo BAL (-138)
Best Odds
Pick made: 2 hours ago
Ed Scimia image
Ed Scimia
Betting Analyst

Trevor Rogers takes the mound after a great 2025 campaign, while the Orioles are looking to rebound from a disappointing year with a lineup that should be far more productive this season. I'm taking Baltimore to get an Opening Day win at home.

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Los Angeles Angels logo LAA @ Houston Astros logo HOU Thu, Mar 26 • 4:10 PM ET
2 Expert Picks 3 Computer Picks
Total Home Runs
Christian Walker logo Christian Walker o0.5 Total Home Runs (+575)
Best Odds
Pick made: an hour ago
Shawn Krest image
Shawn Krest
Betting Analyst

Christian Walker tied for Houston’s spring homer lead and went deep against Soriano in 2024. He's 3-for-9 with a 1.000 OPS in limited matchups with the Angels starter. The most likely candidate to surrender a homer in this game isn’t a starter, though — it’s the Angels’ bullpen. L.A. relievers gave up as many leads as they preserved last year. Their new additions — Drew Pomeranz, Brent Suter and Jordan Romano — were homer prone, particularly vs. right-handed batters. 

Spread
Houston Astros logo HOU -1.5 (+122)
Best Odds
Pick made: 1 hours ago
Shawn Krest image
Shawn Krest
Betting Analyst

Hunter Brown allowed no earned runs in more than 25% of last year’s starts, and allowed just four ER in four Spring Training outings. Carlos Correa plays his first opener for Houston since 2021. His OPS+ jumped from 94 to 117 after returning at last year’s deadline.

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Detroit Tigers logo DET @ San Diego Padres logo SD Thu, Mar 26 • 4:10 PM ET
2 Expert Picks 1 Computer Pick
Total Home Runs
Riley Greene logo Riley Greene o0.5 Total Home Runs (+360)
Best Odds
Pick made: 2 hours ago
Tom Oldfield image
Tom Oldfield
Betting Analyst

I’ll double down on Greene for the HR prop, too. He crushed 36 dingers last season, with 32 of those coming off righties. That’ll put Pivetta under pressure here, and the Detroit slugger hit more homers on the road than at home in 2025. Petco Park isn’t the easiest place to nail the long ball, but Greene’s power overrides that.

Moneyline
Detroit Tigers logo DET (-134)
Best Odds
Pick made: 2 hours ago
Tom Oldfield image
Tom Oldfield
Betting Analyst

After the Tigers’ late-season collapse last year, it’s easy to forget their scorching 29-15 start. I see Detroit flying out of the traps again here – and Skubal, coming off a 2.21 ERA and 0.89 WHIP in 2025, should love the pitcher-friendly conditions at Petco Park.

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Boston Red Sox logo BOS @ Cincinnati Reds logo CIN Thu, Mar 26 • 4:10 PM ET
2 Expert Picks 2 Computer Picks
Moneyline
Boston Red Sox logo BOS (-158)
Best Odds
Pick made: 3 hours ago
Rohit Ponnaiya image
Rohit Ponnaiya
Betting Analyst

Both starters struggled in Spring Training, with Garrett Crochet posting a 7.36 ERA and Andrew Abbott pitching to a 11.72 ERA. Normally I don't much put much stock in how veterans throw in the preseason but Abbott also fell off toward the end of last year, logging a 4.21 ERA with a .264 OBA in his final 10 starts. I have more faith in Crochet who was the AL Cy Young runner up last year after being named an All Star the previous season. I also rate Boston's lineup slightly better despite losing Alex Bregman. Top-to-bottom the Red Sox have fewer holes than the Reds who have unproven hitters outside of Eugenio Suarez and Elly De La Cruz. 

Total Home Runs
Roman Anthony logo Roman Anthony o0.5 Total Home Runs (+390)
Best Odds
Pick made: 3 hours ago
Rohit Ponnaiya image
Rohit Ponnaiya
Betting Analyst

Roman Anthony is viewed as a future star and seemed on the verge of a breakout last year before an oblique injury ended his season. Anthony's hard-hit rates and exit velocities suggest he can be an elite power hitter.  He also boasts strong reverse platoon splits. which will help him against Reds southpaw Andrew Abbott today. Anthony impressed at the World Baseball Classic and getting his home run prop at +390 at a hitter friendly park could look like a steal in a few months.

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Texas Rangers logo TEX @ Philadelphia Phillies logo PHI Thu, Mar 26 • 4:15 PM ET
2 Expert Picks 2 Computer Picks
Total Home Runs
Adolis Garcia logo Adolis Garcia o0.5 Total Home Runs (+480)
Best Odds
Pick made: 4 hours ago
Neil Parker image
Neil Parker
Betting Analyst

Garcia spent the offseason working with the Philadelphia coaching staff, and he hit a pair of homers with a solid .388 wOBA and .858 OPS during spring training. Even with his production dropping the past two years, Garcia hit a respectable 44 homers after launching 97 from 2021-2023.

Spread
Philadelphia Phillies logo PHI -1.5 (+146)
Best Odds
Pick made: 4 hours ago
Neil Parker image
Neil Parker
Betting Analyst

Phillies southpaw Cristopher Sanchez is third in ERA and fourth in xFIP among qualified starters over the past two seasons, and the Rangers enter ranked 24th in wOBA and 20th in ISO against lefties during the same stretch. I’m anticipating Sanchez picking up where he left off and holding the Rangers in check today, while the Philly offense does enough damage to pick up a convincing win.

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Tampa Bay Rays logo TB @ St. Louis Cardinals logo STL Thu, Mar 26 • 4:15 PM ET
3 Expert Picks 3 Computer Picks
Total RBIs
Junior Caminero logo Junior Caminero o0.5 Total RBIs (+115)
Best Odds
Pick made: 3 hours ago
Andrew Caley image
Andrew Caley
Senior Betting Analyst

Junior Caminero is coming off a breakout campaign where he swatted a massive 45 home runs with 110 RBIs. He opens 2026 with a great matchup against Matthew Liberatore. The Cardinals' lefty gives up a lot of hard contact, ranking in the 14th percentile in average exit velocity.

Total Home Runs
Yandy Diaz logo Yandy Diaz o0.5 Total Home Runs (+450)
Best Odds
Pick made: 7 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

Diaz has belted 61 home runs across the last three seasons. He’s also clubbed 41 career bombs off left-handers and 59 jacks against righties during his nine-year career.

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Arizona Diamondbacks logo AZ @ Los Angeles Dodgers logo LAD Thu, Mar 26 • 8:30 PM ET
4 Expert Picks 2 Computer Picks
Total Home Runs
Freddie Freeman logo Freddie Freeman o0.5 Total Home Runs (+450)
Best Odds
Pick made: 4 hours ago
Quinn Allen image
Quinn Allen
Betting Analyst

Zac Gallen gets the ball, and Freeman is 7-for-27 lifetime against him with a pair of long balls. Sixteen of Freddie Freeman's homers in 2025 were off right-handers, and Gallen gave up 31 bombs last year —12 of them to left-handed batters. 

Strikeouts Thrown
Yoshinobu Yamamoto logo Yoshinobu Yamamoto o5.5 Strikeouts Thrown (-136)
Best Odds
Pick made: 4 hours ago
Andrew Caley image
Andrew Caley
Senior Betting Analyst

Yoshinobu Yamamoto dominated this D-backs lineup last season. Current Arizona players have combined for a 32.1% K-rate against Yamamoto, with strikeout totals of 4, 9, 10, and 7 in four games.

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Cleveland Guardians logo CLE @ Seattle Mariners logo SEA Thu, Mar 26 • 10:10 PM ET
4 Expert Picks
Total Home Runs
Cal Raleigh logo Cal Raleigh o0.5 Total Home Runs (+285)
Best Odds
Pick made: 1 hours ago
Shawn Krest image
Shawn Krest
Betting Analyst

If anyone is going to homer in this game, it will be Cal Raleigh, MLB’s reigning home-run leader, playing in his home opener. Bibee’s struggles with the long ball make this an even better bet

Spread
Seattle Mariners logo SEA -1.5 (+126)
Best Odds
Pick made: 1 hours ago
Shawn Krest image
Shawn Krest
Betting Analyst

Cleveland's offense struggled throughout 2025 and will draw a tough matchup in Mariners right-hander Logan Gilbert tonight. Combine that with Tanner Bibee's uneven results while facing a strong Seattle lineup, and the home team wins by multiple runs.

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