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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 28, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

PHI logo
PHI
PHI

3.84 @ 4.36

ATL
ATL logo
ATL

Phillies vs Braves · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

PHI logo
PHI
PHI

3.84

+168

o6.5 -120

+1.5 -129

ATL logo
ATL
ATL

4.36

-186

u7.5 -179

-1.5 +120

Chi. White Sox @ Houston
Matchup Stats

Predicted Score

CHW logo
CHW
CHW

4.48 @ 4.77

HOU
HOU logo
HOU

White Sox vs Astros · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHW logo
CHW
CHW

4.48

+115

o8.0 -115

+1.5 -175

HOU logo
HOU
HOU

4.77

-122

u8.5 -115

-1.5 +160

Boston @ NY Yankees
Matchup Stats

Predicted Score

BOS logo
BOS
BOS

3.89 @ 4.08

NYY
NYY logo
NYY

Red Sox vs Yankees · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

BOS logo
BOS
BOS

3.89

+122

o6.0 -125

+1.5 -175

NYY logo
NYY
NYY

4.08

-136

u6.5 -115

-1.5 +170

Chi. Cubs @ San Diego
Matchup Stats

Predicted Score

CHC logo
CHC
CHC

4.76 @ 4.45

SD
SD logo
SD

Cubs vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHC logo
CHC
CHC

4.76

+110

o7.0 -115

+1.5 -182

SD logo
SD
SD

4.45

-124

u7.5 -122

-1.5 +180

Philadelphia Phillies image thumbnail PHI @ Atlanta Braves image thumbnail ATL Tue, Sep 29 • 2:00 PM ET
Total
Philadelphia Phillies image thumbnail Atlanta Braves image thumbnail o6.5 (-120)
Best Odds
Pick made: 7 hours ago
Neil Parker logo
Neil Parker
Betting Analyst

This Over 6.5 is recommended to -130 because Atlanta ranked 11th in wOBA and 10th in ISO while averaging 4.8 runs per game at home, so the Braves are set up for success against the patchwork-pitching approach from Philly in Game 1. Additionally, the Phillies finished fifth in wOBA and second in xwOBA with the second-lowest strikeout rate against left-handed pitchers in the second half, so I anticipate Philadelphia also chipping in runs Tuesday afternoon.

Moneyline
Atlanta Braves image thumbnail ATL (-190)
Best Odds
Pick made: 7 hours ago
Neil Parker logo
Neil Parker
Betting Analyst

With the Philadelphia rotation taxed after battling to their final game to secure a postseason berth, I’d recommend the Atlanta moneyline to 68%. Additionally, Braves lefty Chris Sale has posted a 3.31 xERA and 3.29 xFIP through eight starts against the Phillies over the past three years. Philly is expected to counter with a bullpen game featuring bulk work from lefty Jesus Luzardo and righty Andrew Painter. Luzardo returned from a shoulder injury for a relief inning Sunday, while Painter sports a discouraging 4.60 xERA and  4.55 xFIP on the road. This gives the Braves a sizable starting-pitching edge in Game 1.

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Chicago White Sox image thumbnail CHW @ Houston Astros image thumbnail HOU Tue, Sep 29 • 5:00 PM ET
Total
Chicago White Sox image thumbnail Houston Astros image thumbnail o8.5 (+103)
Best Odds
Pick made: an hour ago
Colby Marchio logo
Colby Marchio
Contributor

The White Sox and Astros are both swinging hot bats at the right time, making the market’s low-scoring expectation intriguing. Houston posted a 117 wRC+, .338 wOBA and .776 OPS during the final week of the regular season, while Chicago posted a 131 wRC+, .358 wOBA and .806 OPS. The White Sox’s pitching situation remains uncertain, and whoever takes the mound won’t exactly inspire confidence. Chicago’s bullpen also owns a 3.55 ERA and 4.59 xERA over its last 21 games while allowing a 42% hard-hit rate. With both offenses clicking, I’m expecting plenty of scoring in this matchup.

Moneyline
Chicago White Sox image thumbnail CHW (+107)
Best Odds
Pick made: an hour ago
Colby Marchio logo
Colby Marchio
Contributor

The White Sox are in a strong spot to jump out early against Astros opener AJ Blubaugh, who owns a 7.71 ERA across 11.2 innings this month. Over his last seven appearances, he’s allowing 2.70 HR/9 with a 70% elevation rate, while opposing hitters own a .303 xBA and .600 xSLG. Chicago’s offense has started to wake up, posting a 112 wRC+, .332 wOBA and .736 OPS in its recent stretch. Erick Fedde or Davis Martin will follow as the bulk reliever, with Fedde preferred after posting a 3.45 ERA over his last five road starts. I’m backing Chicago as a Game 1 underdog.

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Boston Red Sox image thumbnail BOS @ New York Yankees image thumbnail NYY Tue, Sep 29 • 8:00 PM ET
Total
Boston Red Sox image thumbnail New York Yankees image thumbnail u5.5 (+116)
Best Odds
Pick made: 3 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

We have two aces on the mound that have dominated this specific matchup throughout the year, with both Schlittler and Tolle rocking a sub-1 ERA against their AL East rival. Yes, Schlittler is the likely Cy Young this season, but Tolle is no slouch - his .199 xBA, 36% chase rate, and 28% K rate this season is among the best in baseball. When you tie in their walk rate (both are issuing the free pass at just a 6% clip), each offense will have to earn it. No matter which angle you attack this one at, it smells like an Under.

Moneyline
New York Yankees image thumbnail NYY (-158)
Best Odds
Pick made: 3 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

Cam Schlittler started against the Boston Red Sox four times across the 2026 MLB season; to say he dominated would be an understatement. Across 24 1/3 innings, he owned a 0.74 ERA while registering 27 strikeouts. Simply put, he was nearly unhittable, and the Boston Red Sox have some work to do if they want to take Game 1 of the Wild Card series. Payton Tolle takes the mound for Boston, and while he's had similar success in this spot in a smaller sample size (0.69 ERA across 13 1/3 innings), I'm leaning toward the New York Yankees' starpower and their ability to hit lefties. The pinstripes actually own better splits here, rocking a .733 OPS against southpaws.

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What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

What kinds of MLB picks do we make?

Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.