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Find the best NFL bets today - Sept. 25, 2026. Free expert and computer picks for every NFL game.
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
26.21 |
-10.5 -109 |
o45.5 -108 |
-575 |
|
|
17.26 |
+10.5 -105 |
u46.5 -115 |
+520 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
20.16 |
-2.5 -112 |
o41.5 -110 |
-142 |
|
|
18.86 |
+2.5 +100 |
u42.5 -110 |
+127 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
15.97 |
+2.5 -102 |
o38.0 -110 |
+120 |
|
|
18.98 |
-2.5 -110 |
u38.5 -110 |
-135 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
22.08 |
+3.0 -115 |
o45.5 -113 |
+132 |
|
|
23.72 |
-3.0 -105 |
u46.5 -115 |
-150 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
20.86 |
+7.5 -115 |
o50.0 -110 |
+295 |
|
|
26.49 |
-7.5 +100 |
u50.5 -115 |
-334 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
19.39 |
+6.5 +100 |
o47.5 -109 |
+260 |
|
|
29.27 |
-6.5 -112 |
u48.0 -108 |
-300 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
21.96 |
-1.5 -114 |
o42.5 -110 |
-125 |
|
|
22.79 |
+1.5 -105 |
u43.5 -115 |
+112 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
23.24 |
-7.5 +100 |
o40.5 -102 |
-340 |
|
|
16.07 |
+7.5 -106 |
u40.5 -109 |
+300 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
24.81 |
-3.5 -105 |
o42.5 -109 |
-175 |
|
|
21.38 |
+3.5 -109 |
u42.5 -105 |
+160 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
20.60 |
+8.5 -110 |
o48.0 -107 |
+350 |
|
|
26.83 |
-8.5 -105 |
u48.5 -114 |
-400 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
20.44 |
-1.5 -105 |
o42.0 -132 |
-120 |
|
|
21.22 |
+1.5 -109 |
u43.0 -115 |
+106 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
24.85 |
-3.5 +100 |
o52.5 -114 |
-175 |
|
|
25.78 |
+3.5 -112 |
u53.5 -110 |
+155 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
20.83 |
+3.5 -120 |
o43.5 -110 |
+154 |
|
|
25.78 |
-3.5 +100 |
u44.0 -110 |
-173 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
22.63 |
+0.0 -139 |
o43.5 -115 |
-134 |
|
|
23.11 |
+1.5 -105 |
u44.5 -110 |
+120 |
Predicted Score
Team |
Predicted Score |
Spread |
Total |
ML |
|---|---|---|---|---|
|
|
22.72 |
-4.5 -110 |
o41.0 -110 |
-225 |
|
|
19.32 |
+4.5 -105 |
u41.5 -110 |
+200 |
The Dolphins have had issues covering tight ends this year with George Kittle securing a touchdown and 80 yards last week, and the combo of Michael Mayer/Jack Bech hauling in nine catches for 55 yards and a score in the season opener. With the Chiefs scheming Kelce open so far this year, expect him to fly past this number, he's done so twice already.
Looking for a slam dunk? It's Kenneth Walker. He was denied three straight times on the 1-yard line a week ago but is in line to score at least once against one of the worst run defenses in football. With the Chiefs likely in cruise control come the second half, look for them to lean on Walker and Emmett Johnson. If you're looking for more value, the team is looking to give the latter "more snaps," which could bode well this week in the touchdown department.
I really wanted Quinshon Judkins at 2.25x against the Panthers, who are getting gashed on the ground. However, getting Denzel Boston at this price after two weeks of cashing still feels long, with a fair price around 3.2x. Judkins has not found any room to run through two games, but Boston already has a 21% target share and a whopping 52% of the air-yard share. The only wide receivers with a bigger AYS are Jaxon Smith-Njigba, Justin Jefferson, and Chris Olave — some big hitters. Boston can run the deep route for a score like he did in Week 1 or catch and run for yards like last week. He's beaten the Jaguars and Bucs. Surely, he can beat the Panthers, who gave up 59 points in Week 1 before having to play the worst QB tandem in the history of the sport in Week 2.
This Judkins Over is in play to 46.5 because Carolina has allowed the highest yards per carry (6.31) to opposing running backs while ranking 29th in run defense DVOA through two weeks. The Cleveland rusher also cleared this total in nine of 14 games last season, and he has handled 75% of running back carries with a 66% snap share to start 2026. Judkins’ go-to role positions him to scamper well Over this number in the soft Week 3 matchup.
Elic Ayomanor might be WR2 facing a Giants defense that is on a short week and dealing with cluster injuries at corner. Davante Adams did whatever he wanted on MNF because of the lack of NFL talent at corner. Ayomanor should not be longer than 5.5x. He's playing better than Calvin Ridley and is getting targeted on 20% of his routes while sitting second on the team in air-yard share at 30%. He also has all of the WR red-zone targets at three through two games, with a TD. It's a longer shot here, but certainly +EV. The only thing knocking it is a bad pass offense, but the Eagles and Jets are a lot different than the Giants, who have allowed a red-zone touchdown on all six of their opponents' trips inside the 20.
Grabbing this -5.5 line before Monday Night Football because I’m expecting the Giants to hang with the Los Angeles Rams in Week 2, and New York will be an even larger home favorite over Tennessee by Sunday afternoon. The Titans were only on offense for 23:35 against the Philadelphia Eagles on Sunday, and QB Cam Ward has thrown for just 6.2 yards per attempt through two weeks. Tennessee also hits the highway for the first time in 2026, and the new-look G-Men put on an offensive clinic in their season opener at MetLife Stadium.
This is one of the higher +EV TD plays, per THE BLITZ projections, which have Hunter Henry at a fair price of 3.05x vs. this 3.5x bargain. I'm not going to try to figure out a muddied New England backfield, but Henry is playing 92% of the snaps, and the injury to rookie Eli Raridon could help open up some more targets. The New England wide receivers are tough to trust, with five of them splitting just 12 targets last week. Henry led the team in routes and targets last week and might be the No. 1 option in the passing game right now. TEs with this kind of route and target volume should be around 3x to score.
TreVeyon Henderson made his season debut for New England in Week 2, garnering 60% of snaps after his backfield mate Rhamondre Stevenson fumbled early on. Henderson finished with 16 carries for 76 yards and while the touches could be better balanced in Week 3, head coach Mike Vrabel didn’t dismiss Henderson’s involvement. With the Jaguars pass rush a problem, the New England run game needs to take heat off Maye and avoid long third downs. Jacksonville isn’t as strong versus the run, including the No. 28 rating in run stop win rate at ESPN. Measuring projections between the Pats two RBs, Henderson holds the most value. His forecasts lean toward 40+ rushing yards with some as high as 57 gains on the ground in Week 3.
With the Bills allowing the fifth-highest EPA per dropback in the second half, I’d recommend this McConkey Over to 60+ receiving yards. He’s been a full participant in practice all week and has a solid 14.6 yards per reception and 13.8 aDoT through two games. Additionally, McConkey has garnered a high-end 23.9% of the team’s air yards with an 18.9% target share. Plus, Buffalo has also surrendered the ninth-highest yards per target (9.16) to opposing wideouts through two weeks.
Depending on how you look at the Chargers’ chances in Orchard Park, you may or may not be onboard with Omarion Hampton getting Over his rushing total. The big spread says the Bolts are playing from behind and passing, but L.A.’s best plan of attack is to run early and often and control the football – not allowing Josh Allen & Co. on the field. Hampton had a nice day in the loss to Vegas, rushing 23 times for 94 yards, and his involvement is the key to Mike MacDaniel’s misdirection-heavy schemes. Buffalo’s run defense continues to be a work in progress (28th in EPA allowed per handoff) and models are positive for Hampton, sitting north of 60 yards with a ceiling of 72. My number is at 67 yards on Sunday.
Even the Jets should find points against a Detroit defense that’s surrendered 71 through two games. The Lions can handle the heavy lifting though. They’ve led the league in home scoring in two straight seasons, have extra rest, and pose a far tougher challenge than anything the Jets have faced so far this season. Including the playoffs, eight of Detroit’s last 10 home games cleared 47.5, averaging 58.1 combined points.
There are a lot of Jets angles I want here. The Lions have been awful at defending the TE position early in the season, as even the Saints had TDs from Juwan Johnson and Noah Fant in Week 1. The problem is that the Jets have a four-TE rotation, with Kenyon Sadiq at 5.1x being a possibility, but I'm looking elsewhere. Adonai Mitchell (4.1x) had 12 targets last week and leads the Jets in target and air-yard share, but I don't want to get cute when Garrett Wilson is 2.5x or better. It's an indoor game with a high total, and Wilson also ranks high on the Covers Anytime TD Value Index. The Jets could put up points against this toothless defense, and a move from 2.8x last week to 2.7x this week isn't enough for the setting and matchup.
The Colts' defense continues to leak, especially its secondary, which has allowed back-to-back 300-yard days from opposing quarterbacks. Stroud is off to a hot start himself, throwing for 627 across his first two games - not bad. Indy is allowing nearly 14 yards per pass completion, which should put us in a great spot to cash this come Sunday.
The Colts own one of the worst red-zone defenses in the NFL, allowing teams to score at a near-70% clip when they reach their 20. This bodes well for Montgomery, who's being used the third-most in the red zone of any other running back in football, totaling six attempts for 19 yards and two touchdowns. Suffice to say when they get down by the goalline, Montgomery is their man.
Jaxon Smith-Njigba faces a banged-up Commanders secondary running one the highest rates of zone coverage through two weeks. Washington is still trying to find its way in the new schemes of DC Daronta Jones, rating near the bottom of the league in many advanced pass defense measurements. That includes rating 30th in DVOA vs. WR1. Smith-Njigba is the top WR vs. zone coverage and projections are positive in DC, with most models coming in above 90 yards – ceiling of 115 – and my number coming out to 95+ receiving yards.
I got this at 3x, and even if Jadarian Price is out, this could close at 2.3x. Even if Price does play, Emanuel Wilson handled more red-zone carries last week than any other running back in football and didn't get a full workload until the second half. Another angle here is that the Seahawks want to run the ball in the red zone. Through two games with Drew Lock, Seattle has run the ball 18 times in the red zone compared to just nine dropbacks. Price is dealing with a chest injury that could keep him out of the hard-yard work in the red zone even if he dresses. Give me the 20-touch back at a long TD price in a positive-game-script matchup against a backup QB.
Burrow has thrown for two or more touchdowns in six of his past eight games for 18 total dating back to 2025, and the Steelers have backfield question marks. Pittsburgh cornerback Jamel Dean practiced Thursday after missing Wednesday’s session with an ankle injury, safety DeShon Elliott is on injured reserve, and Joey Porter Jr.'s status continues to be clouded by contract disputes after missing the first two weeks of the season.
The Bengals haven’t looked to Higgins in the red zone yet in 2026, and I’m anticipating that to change following consecutive seasons with double-digit touchdowns. Higgins garnered 19.8% and 19% of the red-zone targets the past two years, and wide receiver Andrei Iosivas (thumb) is also out of the lineup. With Pittsburgh set to have its hands full with star wideout Ja'Marr Chase, Higgins stands to see softer coverage in Week 3, too.
I got this at 3x and think the fair price should be around 2.65x. Deebo Samuel led the team in route share in a similar spot last week as a huge favorite. The 49ers still had a 4.4% PROE (eighth best) despite the positive game script, which keeps me hopeful that Brock Purdy will keep slinging it. The overall play volume wasn't huge, but Samuel tied for the team lead in targets and had a rush, which was his second in two weeks. Samuel could have a path to more targets in Week 3 with Demarcus Robinson out and Mike Evans becoming more questionable after being a DNP at practice Wednesday. Purdy is playing at an MVP level, and Samuel has a role around the goal line, as he is tied for the team lead in RZ targets with three and has one score. If Evans sits, this could close as short as 2.4x or 2.5x.
Defensive masterminds Todd Bowles and Brian Flores send extra pass rushers more than most, which has me measuring just how the respective QBs will handle the heat. Baker Mayfield has been solid versus the blitz during this time in Tampa, with an uncanny ability to sneak away from pressure and either make a play with his legs or squeeze in a release pass. Kyler Murray is expected to be under center after having his Vikings debut cut short due to a concussion in Week 1. Murray hasn’t been great against blitzes during this career and had only 11 full-speed snaps (five dropbacks) in Kevin O’Connell’s offense before getting hurt. We’re getting Tampa Bay at a discount. It was originally a 1.5-point home favorite on the look-ahead market and sat at that same spread before the results of Week 2.
We're seeing two mediocre offenses against two top-10 defenses in Week 3. The Vikings have had to play mistake-free football on both sides of the ball - their defense has allowed an average of just 12.5 points per game as a result. It's also one of the best red-zone defenses this year, allowing a touchdown on just 12% of trips inside the 20. With positive regression looming for the Bucs' defense against Murray and Co. I'm projecting this total to close closer to 40.5.
Baltimore should come out swinging after scoring just 17 against New Orleans. Dallas ranks 28th in yards allowed per rush attempt and has surrendered a league-worst 68% third-down conversion rate against the Giants and a Commanders team that lost Jayden Daniels. That’s a juicy setup for Derrick Henry and Lamar Jackson. The Ravens still rank second in yards per play, and this matchup gives them every chance to look more like the team that hung 41 on Indianapolis in Week 1.
This was a tough one. I wanted Lamar Jackson, as the Cowboys are giving up the most QB rushing yards to opposing QBs by a mile, but +175 isn't a price I want to pay when it went from 3.6x to 2.85x to this week's 1.75x. It's priced in. Rashod Bateman midweek is appetizing, but I don't want to be holding a 2.75x if Zay Flowers comes back. I have to go back to Jake Ferguson at 3.65x after a cash last week and two red-zone TDs. He is still the No. 3 in the passing game, but has a prominent goal-line role with three of the team's seven RZ pass attempts to tight ends and wide receivers. Dallas had the No. 1 PROE in Week 2 at 13.8%. I'd play Ferguson to 3.40x.
I have to back the arm of Tyler Shough and his league-leading passing yards, but it's not Chris Olave I want — it's Devaughn Vele and his 95% snap share and 90% route share in an indoor game. Vele is a clear No. 2 in this offense and is working with a 20% target share from a quarterback who has thrown for 250+ yards in back-to-back games despite slow first halves. The wide receiver has 16 targets over two games, turning them into 12 catches for 133 yards and a TD. He's also received at least one RZ target in both games. It's another indoor game that projects to be faster and more pass-efficient, and I'm not sure this Las Vegas offense is as strong as its numbers suggest. I got this at 3.95x and would play to 3.5x.
Vegas' new defensive coordinator Rob Leonard is creating tremendous pressure with his front four (No. 1 pressure rate despite blitzing on only 22% of snaps), collecting eight sacks and 10 QB hits. The Raiders now set their sights on second-year QB Tyler Shough. His PFF profile doesn’t paint a pretty picture under pressure. As a rookie, Shough was night and day when kept clean vs. under duress, rating 27th among qualifying QBs. The 2026 season produces a similar split, rating No. 5 when clean but 18th under pressure. It just so happens an already stressed New Orleans offensive line will be without starting LT Kelvin Banks for a while due to an ankle injury in Week 2. The Saints pass protection has already allowed eight sacks and ranks 28th in pass block win rate.
This might seem short, but I have this fair price much closer to even money. Matthew Stafford had no interest in passing to anyone but Davante Adams last Monday, even with the injuries to Puka Nacua and Jordan Whittington, who have been DNPs early this week. Adding to the pass-catcher injuries, Colby Parkinson is dealing with a knee injury. Parkinson played 70% of the snaps in Week 2 and was used more as a blocker, which could be a downgrade for the run game. Stafford was also happy to keep passing in the second half in a game that was already over when Jaxson Dart left. Adams was a beast against a bad secondary, putting up 195 yards and two TDs on 10 targets. He has a 28% target share heading into the Sunday nighter. Adams is also arguably the best red-zone pass-catching wide receiver in football. He tied for the league lead in RZ targets last year with 32 despite playing in only 14 games. He should be even money here, and even Patrick Surtain doesn't scare me.
Los Angeles quarterback Matthew Stafford not only faces one of the stingiest secondaries in the league but could do so without some of his top options. Wide receivers Puka Nacua and Jordan Whittington are questionable along with ailments to tight ends Colby Parkinson and Terrance Ferguson. Denver is a tough team to pass against, even when you’re receiving corps is healthy. The Broncos rate Top 12 in many advanced pass defense metrics, including opponent success rate per dropback. Stafford may not have to do much downfield if Denver can’t slow down the Rams’ rushing game. The Broncos have been bullied on the ground in the first two contest and we could see Stafford handing off at a higher rate. His Week 3 projections don’t go beyond 250 yards with my number sit short of 240 passing yards from Stafford on Sunday night.
I'll be backing the Philadelphia Eagles at -4.5 in this one, as I price them closer to a 6-point favorite against the Chicago Bears. I'm not going to lie, the side I choose always comes down to the numbers, but as a football fan, I'm thrilled that my edge in the projections is with the Eagles instead of Tyson Bagent/Case Keenum and the Bears. The line has moved six points from Bears -1.5 to Eagles -4.5 following Caleb Williams' injury and the downgrade to Bagent/Keenum. But I don't think the market has adjusted enough for this specific matchup against an Eagles defense coached by Vic Fangio and loaded with playmakers. This isn't a Williams-to-Bagent/Keenum downgrade against the Tennessee Titans.
The Eagles receivers are about to see their highest rate of man-to-man coverage in Chicago. And while DeVonta Smith is a man killer, fellow WR Dontayvion Wicks is also great in one-on-ones. He rates out 16th vs. man at PFF. The Bears will send doubles at Smith, leaving Wicks in single coverage and likely facing a CB way down the depth chart. Chicago has injuries in the secondary stacking up and it looks like Tyrique Stevenson is the latest to go down. Wicks has posted two 70+ efforts vs. zone centric schemes in the first two games and projections lean toward 40+ with a ceiling of 51 yards.
Our experts and prediction models are hard at work analyzing the data. Check back shortly for today's picks, or explore our Computer Picks for inspiration.
For every matchup in an NFL season, our NFL computer produces selections for a variety of different betting angles. Our computer picks are based on a proprietary algorithm that values each team in the current week to produce moneyline, spread, and point total selections.
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