Diamondbacks vs Yankees Prediction, Picks & Odds for Today’s MLB Game

The Yankees' offense is on fire, and the Diamondbacks' Zac Gallen won't be able to cool their (torpedo) bats tonight, as our MLB betting picks explain.

Tom Oldfield - Betting Analyst at Covers.com
Tom Oldfield • Betting Analyst
Apr 2, 2025 • 12:34 ET • 4 min read
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This article contains predictions for an old game!

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Arizona Diamondbacks MLB Zac Gallen
Photo By - Imagn Images. Arizona Diamondbacks pitcher Zac Gallen winds up.

It’s been one long home run barrage for the New York Yankees so far this season, and they’ll look to keep the torpedo bats firing tonight against the Arizona Diamondbacks. 

Despite more fireworks last night, New York suffered its first loss of 2025, falling 7-5 to Arizona after Eugenio Suarez’s late grand slam. But my Diamondbacks vs. Yankees predictions and MLB picks for this April 2 clash expect the Bronx Bombers to rebound here at Zac Gallen’s expense.

Diamondbacks vs Yankees prediction

My Diamondbacks vs Yankees best bet: Zac Gallen Over 2.5 earned runs allowed (+100 at bet365)

The New York Yankees have started the season like a team that knows its offense has to paper over some cracks in the pitching staff. With 18 home runs, an MLB record through four games, the Yankees clearly got the memo.

It’s not as if this has just been an Aaron Judge onslaught either. Judge has led the way with four homers, but nine different New York batters have recorded dingers already this season — another record — and I’m wagering on more of the same from the Yankees tonight against Arizona Diamondbacks starter Zac Gallen.

Gallen is coming off a shaky Opening Day start that yielded four earned runs in four innings of work, and now has to navigate an explosive New York lineup that’s flown out of the gates despite starting the year with Giancarlo Stanton on the IL.

The D-Backs starter, who boasts a 3.32 career ERA, should be sharper here, but this is still a tough spot for the righty. Dating back to last season, he’s given up at least three earned runs in 10 of his past 17 starts.

Meanwhile, the Yankees have hit the team total Over in 20 of their last 31 home games, and they’ve already scored 41 runs in this season-opening homestand.

The long ball threat makes this Over just a few swings away, with New York turning five hits into five runs last night, and I expect Gallen to be under pressure early in this one.

Diamondbacks vs Yankees same-game parlay (SGP)

Zac Gallen Over 2.5 earned runs allowed

Yankees moneyline

Aaron Judge Over 0.5 RBI

I’m doubling down on the New York offense here and banking on run support guiding Carlos Rodon to another win. Rodon allowed one run on four hits in his first start of the year and posted a 3.96 ERA last season. He gave up just two runs through 5 1/3 innings against the D-backs last April.

Arizona finished with a 45-48 mark against teams with a record above .500 in 2024 and needed a grand slam to escape with a victory last night. Though the D-backs have covered the run line in 31 of their past 47 road outings, the Yankees are 19-12 in their last 31 contests, and I see them edging what could be a high-scoring contest.

Even with the Yankees getting huge production from the supporting cast, Judge remains the main man. He can go yard at any point, but he’s also benefitting from steady table-setting from the bottom half of the order and Paul Goldschmidt above him. 

Judge went 0-for-4 last night, but he’s already driven in 11 runs this year (tied for first in the majors), and I’m rounding out my SGP by picking him to serve up another RBI here at Yankee Stadium.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Diamondbacks vs Yankees odds

Diamondbacks vs Yankees live odds

Diamondbacks vs Yankees opening odds

  • Moneyline: Arizona +116 | New York -128
  • Run line: Arizona +1.5 | New York -1.5
  • Over/Under: Over 8.5 | Under 8.5

Diamondbacks vs Yankees trend

The Over is 68-37 in the Diamondbacks’ last 105 contests. Find more MLB betting trends for Diamondbacks vs. Yankees.

How to watch Diamondbacks vs Yankees and game info

Location Yankee Stadium, Bronx, NY
Date Wednesday, 4-2-2025
First pitch 7:05 p.m. ET
TV ARID, AmazonPV
Diamondbacks starting pitcher Zac Gallen
(0-1, 9.00 ERA)
Yankees starting pitcher Carlos Rodon
(1-0, 1.69 ERA)

Diamondbacks vs Yankees latest injuries

Diamondbacks vs Yankees weather

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Tom Oldfield - Covers
Betting Analyst

Tom Oldfield’s sports writing journey over the past 20 years has taken him from the Premier League and Champions League to the NFL, NBA, WNBA and MLB, with a wide range of articles and betting previews. Tom has worked closely with London’s Sportsbeat sports news agency as well as (thrillingly!) covering the Toronto Raptors’ 2019 NBA championship run, and he has appeared on BBC World Service and The Back Page podcast.

A graduate of the University of Nottingham in the UK, he is the author of biographies on Cristiano Ronaldo, Rafael Nadal, Gary Neville and Cesc Fabregas, and he co-authors a long-running series of children’s soccer books with his brother, Matt.

As a regular bettor across the top sports leagues, particularly with FanDuel and bet365, he is well versed on all the major markets and the next big game is rarely far from his thoughts. The best betting advice he has received is to monitor multiple sportsbooks to grab the best possible value.

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