Liberty vs Oregon Prediction, Picks & Odds for Friday’s March Madness Game

Liberty seems like an enticing upset pick, but a terrible travel schedule mixed with the size of Oregon will help the Ducks cover.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Mar 20, 2025 • 16:36 ET • 4 min read

NCAAB

Match starts: 13 hrs
ORE
37 %
LIB
63 %
EXPERT PICK - SPREAD
Oregon -6.5 (-110) Oregon -6.5 (-110)
Read Analysis
Nate Bittle Oregon Ducks NCAAB
Photo By - Imagn Images. Bittle cheers on his teammates.

The first round of the NCAA Tournament wraps up on Friday night with a clash between the No. 12 seeded Liberty Flames and No. 5 seed Oregon Ducks.

This is an East Region game but will take place in Seattle and my Liberty vs. Oregon predictions expect that to make a difference.

Here are my free March Madness picks for this March 21 clash, with tipoff at 10:10 p.m. ET.

Who will win Liberty vs Oregon?

There are a lot of March Madness brackets where Liberty is a trendy upset pick, which is understandable since Oregon has looked vulnerable, and the Flames are one of the best 3-point shooting teams in the country.

If they catch fire from deep, can they pull off the upset? Sure, but relying on threes is a high-variance strategy that can backfire if your shots aren't dropping.

With Oregon's sold 3-point defense and a huge (no pun intended) size advantage, I don't see the Flames having as much success as usual from beyond the arc.

When you also add in their tough situational spot, flying to Seattle for a late tip-off, the West Coast based Ducks will get the win.

Liberty vs Oregon prediction

My best bet: Oregon -7 (-110 at bet365)

With 12/5 seed upsets now a narrative the public is looking for, bettors sometimes come in hard on No. 12 seeds, which can lead to us getting pretty good lines for the favorite.

This is a brutal travel spot for the Liberty Flames, who fly from Virginia to Seattle for a 10 p.m. ET tipoff. Meanwhile, the Oregon Ducks will be right at home in the Pacific Time Zone. 

The Flames are perimeter-oriented and rank fifth in the country in 3-point percentage (39.5%) and third in 3-point defense (28%).

That said, it's one thing to get open looks from deep against Conference USA foes and another to get them against an athletic, high-major squad like Oregon. The Ducks hold foes to 31.6% shooting from the arc, and head coach Dana Altman will be able to gameplan against a one-dimensional attack.

Liberty also has one of the smaller lineups in Div 1 and is just 298th in rebounding rate (47.6%). The Ducks are 110th in rebounding rate (51.4%), and that's banging against the sizable frontcourts in the Big Ten.

With seven-foot center Nate Bittle and a big group of forwards, Oregon should control the paint. 

Liberty vs Oregon same-game parlay (SGP)

Oregon -6.5

Jayvon Maughmer Under 1.5 threes

Nate Bittle Over 7.5 rebounds

For Oregon to cover this spread, it'll need to limit the Flames from behind the arc and prevent second chances on the offensive glass.

Liberty wing Jayvon Maughmer takes more than half of his shots from beyond the arc but he converts a modest 32.8% of them. He has knocked down fewer than 1.5 threes in 14 of his last 18 games and has an ugly 30.6 3PT% over that span.

Bittle has pulled down at least eight boards in three straight and he's coming off an 11-rebound performance against a Michigan State squad that usually dominates the glass.

He'll have a productive day inside against Liberty, who is 347th in the country in average height, according to KenPom.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your March Madness ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 15+ points!

Learn more about this feature, and all of bet365's offerings, with our comprehensive bet365 review.

21+. Gambling problem? Call 1-800-GAMBLER.

Liberty vs Oregon odds

Liberty vs Oregon live odds

Liberty vs Oregon opening odds

  • Spread: Liberty +6.5 | Oregon -6.5
  • Moneyline: Liberty +230 | Oregon -280
  • Over/Under: Over 140.5 | Under 140.5

Odds courtesy of bet365

Liberty vs Oregon betting trend to know

The Under is 7-1 in Oregon's last eight games. Find more college basketball betting trends for Liberty vs. Oregon.

Covers 100K MM Contest

How to watch Liberty vs Oregon

Region East
Location Climate Pledge Arena, Seattle, WA
Date Friday, 3-21-2025
Tip-off 10:10 p.m. ET
TV truTV

Liberty vs Oregon key injuries

Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than any analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics and Oscar odds. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

You can catch Rohit breaking down every UFC event with Joe Osborne on "P4P Picks" on the Covers YouTube channel and he also has regular appearances on "Before You Bet" with Joe. In addition, he's a regular guest on "By The Book" on the Monumental Sports Network and makes guest appearances on VSIN's "The Handle" and CBS Sports.

Rohit primarily makes his bets at bet365, which offers a wide variety of prop markets, but also has accounts at several others so he can shop around for the best prices. For Rohit, bankroll management is key. He believes you should never bet what you can't afford to lose and maximize those few betting opportunities where books misprice a line.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo