Indiana vs Ohio State Prediction and Picks for College Football Week 13

Although the Hoosiers' scoring hasn't been a problem in 2024, they're set for a taste of humble pie when they take on the No. 1 ranked defense in the nation.

Douglas Farmer - Betting Analyst at Covers
Douglas Farmer • Betting Analyst
Nov 21, 2024 • 19:52 ET • 4 min read

NCAAF

Match starts: 33 hrs
OSU
37 %
IU
63 %
EXPERT PICK - TOTAL
u52.5 (-110)
Read Analysis
Jack Sawyer Ohio State Buckeyes NCAAF
Photo By - Imagn Images. Ohio State Buckeyes defensive end Jack Sawyer celebrates after a fumble recovery.

Some unexpected late-week line movement has made this weekend’s biggest game all that much more intriguing. The Ohio State Buckeyes are suddenly only 10-point favorites against the Indiana Hoosiers.

Some might see that and assume significant value on the Buckeyes, but my Indiana vs. Ohio State predictions will focus on the piece of this market that did not move.

Find out more in my college football picks for Saturday, November 23.

Indiana vs Ohio State prediction and best bet

My best bet
Under 52.5 (-110 at BetMGM)
Picks made at time of writing may not reflect live odds.

My analysis
As of Thursday morning, Ohio State was a 13.5-point favorite. In the evening, it was still at -12.5. 

And then it quickly plummeted to -10.

Why?

That initial move could pretty quickly be ascribed to natural late-week line movement sparked by raised limits at many sportsbooks. That increased action firms up the week’s lines, removing any value long before the weekend.

But the second move, from -12.5 to -10? That was a surprise.

Could it be because Ohio State center Seth McLaughlin tore his Achilles in practice this week? That was first reported on Tuesday, so the reaction to it should have been included in the initial move.

Simply enough, the “Why?” of this uncertain move is unclear, but McLaughlin’s absence is the most obvious explanation. Now think further.

Losing your starting center, when you already have some concerns at left tackle due to injury, could provide a hitch in your offense. Indiana’s defense does not have a clear weakness, so anything that knocks the Buckeyes off their usual tendencies could compend. Offensive coordinator Chip Kelly does not have a particular angle to exploit as compensation.

All that said, this total did not move amid those line moves. It remained at 52.5.

A move by more than a field goal in the spread because of one particular thought should have also influenced the total. Doubting Ohio State’s offense would not impact the other side of the ball.

As explosive as the Hoosiers’ offense has been this season, it is facing arguably the best defense in the country. What Michigan did in holding Indiana to 20 points last week, Ohio State will exacerbate much further.

This newfound wonder about the Buckeyes’ offense appears to have impacted the spread. It also should have cut into the total. Since it didn’t, let’s embrace that value.

Indiana vs Ohio State same-game parlay (SGP)

Under 52.5

Will Howard anytime touchdown

Kurtis Rourke 1+ passing touchdowns

Asking veteran quarterback Will Howard to carry the ball where it matters most should help the Buckeyes hide some of these offensive-line worries, allowing the Ohio State running backs to chip at Indiana’s defensive front seven.

That was the expectation when the Buckeyes visited Penn State, and it became reality until Howard lost control of the ball six inches from the goal line. An important reality of betting on football is not to overreact to the bounces of an oblong ball.

Howard has scored six times this season, and it would be seven if not for that fluke.

As for including Indiana quarterback Kurtis Rourke in this same-game parlay, it is somewhat of an expectation that the Hoosiers will score at some point. That will most likely come from the quarterback with at least one passing touchdown in every game this year. 

It is also an expectation that if and when Indiana is trailing, it will turn to the air to try to catch up quickly.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Indiana vs Ohio State odds

Indiana vs Ohio State live odds

Indiana vs Ohio State opening odds

  • Indiana vs. Ohio State spread: Ohio State -11.5
  • Indiana vs. Ohio State moneyline: Indiana +310, Ohio State -400
  • Indiana vs. Ohio State Over/Under: 52.5

Odds courtesy of BetMGM

Indiana vs Ohio State spread and Over/Under analysis

  • This spread opened with Ohio State favored by 12, jumping to -12.5 by Monday and then reaching -13.5 on Wednesday.
  • A conspiracy theorist would wonder if there is secretly another Buckeyes’ injury that led to the Thursday move to -10 from -12.5.
  • This total opened at 54.5 on Sunday afternoon and nearly immediately fell to 52.5. From there, it remained at 52.5 until it briefly toggled to 51.5 midweek.

Indiana vs Ohio State betting trend to know

The Buckeyes have been in five notably massive games in the last two seasons, going 3-2 outright in them. The Under easily cashed in all three of those wins by an average of 18.3 points. Find more college football betting trends for Indiana vs Ohio State.

Indiana vs Ohio State game info

Location: Ohio Stadium, Columbus, OH
Date: Saturday, 11-23, 2024
Kickoff: 12:00 p.m. ET
TV: FOX

Indiana vs Ohio State latest injuries

Indiana vs Ohio State weather

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Douglas Farmer
Betting Analyst

Douglas Farmer spends his days thinking about college football and his nights thinking about the NBA. His betting habits and coverage follow that same pattern. He covered Notre Dame football for various outlets from 2008 to 2024, most notably spending eight seasons as NBC Sports’ beat writer on the Irish. That was also when his gambling focus took off. Knowing there were veteran beat writers with three decades more experience than he had, Douglas found his niche by best recognizing Notre Dame’s standing in each year’s national landscape, a complex tapestry most easily understood and remembered via betting odds.

In 2021, that interest created a freelance opportunity with Covers, a role that eventually led to Douglas joining the company full-time in 2023. In the fall, Douglas will place five or six dozen bets each week, a disproportionate amount via BetRivers because the operator tends to have lines slightly different than the rest of the market. The same can be said of Circa Sports’ futures markets.

While Douglas is an avid NBA fan and covers the league throughout the year, the vast majority of his bets are on college football, because that is the biggest key to sports betting: Know what you do not know.

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