Diamondbacks vs Giants Prediction, Picks & Odds for Tonight’s MLB Game

Ryne Nelson has emerged as a legitimate mid-rotation starter for the Diamondbacks and he draws a scuffling Giants offense by the Bay tonight. With Arizona's offense one of the best around, the road team is in a great spot to pull out the win.

Neil Parker - Analyst at Covers.com
Neil Parker • Betting Analyst
Sep 3, 2024 • 11:43 ET • 4 min read
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This article contains predictions for an old game!

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The Arizona Diamondbacks and San Francisco Giants start a three-game set at Oracle Park tonight. Arizona has been hot at the dish, and righty starter Ryne Nelson has been keeping opposing hitters in check down the stretch. 

My  Diamondbacks vs. Giants predictions are calling for Arizona to keep the good times rolling against the struggling San Francisco bats in the series opener tonight.

My full MLB picks dig deeper into the matchup below.

Diamondbacks vs Giants prediction

My best bet
Diamondbacks moneyline (-112 at Pinnacle)

My analysis

Arizona Diamondbacks righty Ryne Nelson has been sneaky good across his past 10 starts with a tidy 2.77 ERA, 0.98 WHIP, and 3.33 xFIP. His 20.4 K-BB% is a high-end mark, and he’s held opposing hitters in check with a .219 batting average, .274 BABIP, and pedestrian 4.9% barrel rate.

The San Francisco Giants aren’t an intimidating opponent, either. San Francisco ranks 24th with a .297 wOBA against right-handed arms for the season, and the Giants are down to a .290 overall mark while sporting the fourth-highest 26.5 K% over the past 30 days. It’s added up to just 3.84 runs per game for The Orange and Black.

It’s been just the opposite for Arizona. The Diamondbacks are dialed in at the dish with an MLB-best .368 wOBA, .364 on-base percentage, .208 ISO, and 6.66 runs per game over the past 30 days.

Additionally, Arizona ranks second in both wOBA (.337) and OBP (.341) against lefties for the season, and it’s southpaw Kyle Harrison’s turn in the rotation today. It just hasn’t been announced if he’ll officially start tonight. Still, I’m confident in the Diamondbacks offense, and Nelson on the hill against the reeling Giants.

I suspect there will be movement to the Arizona side of this moneyline ahead of the opening pitch regardless of who is announced as the Giants starter.

Diamondbacks vs Giants same-game parlay (SGP)

Diamondbacks moneyline

Diamondbacks TT Over 3.5

Ryne Nelson Over 17.5 outs

All three legs are correlated and align with the case for the best bet. Arizona has scored four or more runs in five of its past six games and, as noted, the Diamondbacks have been an elite offense over the past 30 days.

Nelson has also recorded 18 or more outs in six of his past seven starts, including four straight. I also value that he is still well behind last year’s 165 2/3 combined innings across the majors and Triple-A, so I don't anticipate a pitch count or innings cap tonight with just 136 1/3 frames in 2024.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Diamondbacks vs Giants odds

Diamondbacks vs Giants live odds

Diamondbacks vs Giants opening odds

  • Moneyline: Arizona +100 | San Francisco -120
  • Run line: Arizona -1.5 (+145) | San Francisco +1.5 (-170)
  • Over/Under: Over 7.5 (-110) | Under 7.5 (-110)

Diamondbacks vs Giants moneyline and Over/Under analysis

  • I’m shocked the Diamondbacks aren’t trading as a larger favorite, and my best guess is it's because of the uncertainty of the San Francisco starting pitcher.
  • Regardless of who starts for the Giants, I expect the money to come in on Arizona throughout the day.
  • There hasn’t been meaningful movement to this total at either Pinnacle or bet365, and both shops have the number at 7.5.

Diamondbacks vs Giants trend

The Arizona Diamondbacks have hit the moneyline in 52 of their last 81 games (+21.70 Units / 21% ROI). Find more MLB betting trends for Diamondbacks vs. Giants.

Diamondbacks vs Giants game info

Location: Oracle Park, San Francisco, CA
Date: Tuesday, 9-3-2024
First pitch: 9:45 p.m. ET
TV: ARID, NBC Sports Bay Area
Diamondbacks starting pitcher: Ryne Nelson
(9-6, 4.22 ERA)
Giants starting pitcher: Kyle Harrison
(7-6, 4.22 ERA)

Diamondbacks vs Giants latest injuries

Diamondbacks vs Giants weather

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Betting Analyst

Neil Parker is, first and foremost, a sports fan. A huge supporter of the Cowboys, Cubs, and Maple Leafs, he has managed to parlay his passion into writing gigs with Sportsbook Review, USA TODAY, theScore, DraftKings Playbook, and RotoWire, among many others. He also co-hosted the Daily Fantasy Edge podcast and can now be seen offering expert golf and hockey advice on Covers’ Before you Bet broadcast.

Neil takes a numbers-based approach to his handicapping and complements his in-depth statistical analysis with a keen eye on the markets to provide the best available odds. He loves to lean on his rolodex of idioms to offset his inner nerd. When it comes to wagering, he throws down on anything that catches his eye at bet365, Betway and BetVictor. He also keeps a close eye on CoolBet because the polar bear brand often has outlier NHL and NFL moneyline prices.

Neil graduated with honors from St. Thomas University in 2007 before completing his BEd at Acadia University in 2010. After teaching a myriad of courses and subjects, he found a groove delivering fun lessons to exceptional learners in non-traditional classroom environments. If his decade-plus teaching run taught him anything about sports betting, it’s to stay the course and use the summer – or offseason – to refresh and prepare to be better in the year to come.

Neil’s top pieces of advice for recreational bettors are to stay within your means and to remember sportsbooks aren’t bank accounts. Don’t be afraid to pull those winnings and treat yourself to a lifetime experience courtesy of a big win.

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