Oklahoma vs UConn Prediction, Picks & Odds for Today’s Women’s March Madness Sweet 16 Game

To say that the Sooners have their hands full would be putting it nicely as they take on the dominant Huskies in Saturday's Sweet 16 showdown.

Aisha Quiñones - Senior Publishing Editor at Covers
Aisha Quiñones • Senior Publishing Editor
Mar 29, 2025 • 14:31 ET • 4 min read
Paige Bueckers UConn Huskies NCAAB
Photo By - Imagn Images. UConn Huskies guard Paige Bueckers (5) reacts after a play.

No. 3 Oklahoma has its tallest task in having the No. 2 UConn Huskies next on deck for the Sweet 16 round of the Women's NCAA Tournament.

Paige Bueckers has officially announced that she will be declaring for the WNBA Draft following this college basketball season. As though the Huskies needed any more motivation, this news will likely push them even more to go out with a bang.

My Oklahoma vs. UConn predictions explain why the Sooners won't be able to measure up to what the Huskies have in store. Let's get into my March Madness picks for Saturday, March 29, before tip-off at 5:30 p.m. ET.

Who will win Oklahoma vs UConn?

This one is a no-brainer. It's the Huskies' game for the taking. UConn has Oklahoma outmatched in every way, except for in the post. The Huskies are in a league of their own when it comes to their elite guards, but post players are a different story.

This is where the Sooners can catch Auriemma's team in a vulnerable position, especially with a one-of-a-kind player such as Raegan Beers —who leads Oklahoma in points (17.5 ppg) and rebounds (9.3 rpg). 

If they're able to keep Beers' performance to a minimum, then they'll be in full control to cruise to the Elite 8.

Oklahoma vs UConn prediction

My best bet: UConn -14.5 (-115 at bet365)

This spread is what it is for a reason. Geno Auriemma's squad has been a force to be reckoned with, and that won't change with game-changers such as Paige Bueckers and Azzi Fudd at the helm.

Let's start with the upcoming No. 1 pick in the WNBA Draft. Bueckers is coming off of a strong 34-point second-round performance where she shot an efficient 14-for-21 from the field against South Dakota State. 

With it being confirmed that this will be the last game of seeing her in a UConn jersey, it's no secret that Bueckers and Co. will want to end this in a special way before she makes the jump to go pro.

Meanwhile, the Huskies will get Fudd back for another season, and this tournament run means something different for her. After missing back-to-back tournament runs due to injuries, Fudd is finally getting her moment to shine for the first time since helping the Huskies battle the South Carolina Gamecocks in the 2022 NCAA Tournament title game.

It's been a long time coming, but Fudd has picked up right where she left off three seasons ago, proving to be the perfect complement to Bueckers as they navigate each opponent with ease so far.

Besides being superior in guard play, there's much deeper meaning to why UConn will walk into this matchup motivated and on a mission. With the Huskies standing on business when it comes to their defense — limiting opponents to just 51.5 points per game — I see that trend continuing, with them finding a way to manage the test of Raegan Beers fairly well.

Oklahoma vs UConn same-game parlay (SGP)

UConn -14.5

UConn 1H moneyline

Under 153.5

No disrespect to OU, but keeping UConn contained will be no walk in the park. Much like my previous point, I don't envision the Huskies having any issues taking care of a spread this wide.

Because of that, I believe that UConn sets the tone early in the first half to stick it to the Sooners before they can even try and get into a solid offensive rhythm.

And these Huskies have stated this multiple times: Defense wins championships. Their top-of-the-line defense will prevent Oklahoma from having a successful night, which will surely keep the game total Under.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your March Madness ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 15+ points!

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Oklahoma vs UConn opening odds

  • Spread: Oklahoma +14.5 (-105) | UConn -14.5 (-115)
  • Moneyline: Oklahoma +850 | UConn -1400
  • Over/Under: Over 153.5 (-110) | Under 153.5 (-110)

Odds courtesy of bet365.

How to watch Oklahoma vs UConn

Location Spokane Veterans Memorial Arena, Spokane, WA
Date Saturday, 3-29-2025
Tip-off 5:30 p.m. ET
TV ESPN

Oklahoma vs UConn key injuries

 Oklahoma: No key injuries.
 UConn: No key injuries.

Not intended for use in MA.
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Aisha Quiñones - Covers
Senior Publishing Editor

Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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