MLB Home Run Props, Picks & Odds Today for April 25: Hip, Hip, Jorge!

Jorge Polanco's power stroke is back after a down year in 2024, and his home run tear should continue tonight vs. struggling Marlins starter Cal Quantrill.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Apr 25, 2025 • 14:25 ET • 4 min read
Jorge Polanco Seattle Mariners MLB
Photo By - Imagn Images. Jorge Polanco of the Seattle Mariners in MLB action.

There’s no better way to kick off a weekend than with some fireworks. I’m talking, of course, about betting home run props.

I’ve found my three favorite MLB player props for Friday night, which include Vladimir Guerrero Jr. breaking out of his home run slump, a sneaky good matchup at Nationals Park, and a Mariners hitter who has returned to form in 2025.

Here are my MLB picks for who will go yard on April 25.

Best MLB home run props today

  • Jays Vladimir Guerrero Jr. 1+ home run (+425)
  • Mets Brandon Nimmo 1+ home run (+380)
  • Mariners Jorge Polanco 1+ home run (+425)

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HR picks for April 25

Vladimir Guerrero Jr. 1+ home run (+425 at DraftKings)

Vladimir Guerrero Jr. is going to start hitting home runs by the bunches. I’m sure of it.

It could start tonight at Yankee Stadium, and it's not just because his 14 career home runs there is his most in any big league ballpark outside of Toronto.

For starters, the Yankees’ SP is Carlos Carrasco, who has been serving up meatballs this season like he’s working at an Italian restaurant. The veteran right-hander has allowed 15 runs on 23 hits and seven walks in just 20 2/3 innings pitched this season. That works out to a 5.14 expected ERA and a .488 xSLG.

He also just isn’t missing a lot of bats. Carrasco ranks in the eighth percentile in whiff rate and the 14th percentile in both hard-hit rate and barrel rate.

Then there is Vladdy. While he just has one dinger on the season, the numbers say a breakout is due. He enters this series ranking in the 92nd percentile or better in expected batting average, average exit velocity, hard-hit percentage, and bat speed. So bigger hits are coming. 

He also has some previous success against Carrasco, going 2-for-6 with a home run. That works out to a .682 xSLG. At this price, I like backing Vladdy to barrel up one of those meatballs tonight.

Brandon Nimmo 1+ home run (+370 at DraftKings)

Kodai Senga and Jake Irvin are facing off when the New York Mets visit the Washington Nationals tonight, so it might not look like a great game to pick home runs for, but the matchup is giving us some underlying value.

Let’s start with the conditions. Nationals Park is ripe for some dingers tonight. The forecast is calling for partly cloudy skies with a 10-12 mile per hour winds blowing out to left-center field. So, there is added chance of going yard tonight.

Next, let’s focus on Irvin. He enters this game with a solid 3.86 ERA, but the advanced numbers say he’s been a little lucky.

The right-hander’s expected ERA is a much uglier 5.01. Irvin also ranks in the 25th percentile or worse when it comes to expected slugging percentage, hard-hit percentage and barrel rate. And there are a few Mets who have barreled him up in the past, including Brandon Nimmo.

While Irvin has been a little lucky, Nimmo has been a little unlucky. The Mets outfielder has a .196 batting average, his xBA is .246, and his .450 xSLG is in the 61st percentile among MLB batters. He also ranks in the 90th percentile in hard-hit rate.

Nimmo is also 3-for-12 with a home run in his career vs. Irvin, good for a .560 xSLG. At this price, I like Nimmo to run into one tonight.

Jorge Polanco 1+ home run (+425 at DraftKings)

It looks like Jorge Polanco is showing us that 2024 was just a blip on the radar, as the Seattle Mariners third baseman has gotten back to his slugging ways in 2025.

He enters tonight’s game against the Miami Marlins hitting .351 with a .963 OPS, and four home runs. But Polanco’s advanced numbers are even more impressive.

Polanco ranks in the  80th percentile in barrel rate, the 84th percentile in hard-hit percentage, the 94th percentile in expected slugging, and the 100th percentile in expected batting average. The bat can play.

And it certainly will tonight, because Polanco will dig in against struggling Marlins starter Cal Quantrill. 

The 30-year-old right-hander has been roughed up so far this season. His numbers basically look like the opposite of Polanco’s. He enters this game with a 7.01 expected ERA, a .342 expected batting average, and a .529 expected slugging. 

So, while Quantrill has only surrendered two home runs this season, he is getting hit hard and often, and it’s just a matter of time before more balls start leaving the yard on him. So, why not tonight? 

  1. Aaron Judge, Yankees +170
  2. Kyle Schwarber, Phillies +320
  3. Ben Rice, Yankees +500

Betting info courtesy of DraftKings

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Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew “Taco” Caley wanted to do was write about sports, something he’s been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS.

These days Andrew’s betting expertise is focused on his favorite teams – the Toronto Blue Jays and Toronto Raptors. He’s also an avid college football fan and bettor. He can’t be friends with you if you don’t appreciate a Service Academy Under. You can also call him Covers’ Sixth Man, as he regularly steps up to guest host Before You Bet and our MLB and NCAAF release shows.

The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It’s not an interesting story. Seriously.

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